Search results for 5970

NFkB p65 (Acetyl Lys221) antibody, Genetex, GTX54951

NFkB p65 (phospho Thr254) antibody, Genetex, GTX54982

NFkB p65 (phospho Thr435) antibody, Genetex, GTX54983

NFkB p65 (phospho Ser276) antibody, Genetex, GTX55113

NFkB p65 (phospho Ser536) antibody, Genetex, GTX55114

NFkB p65 (phospho Ser529) antibody, Genetex, GTX55127

NFkB p65 (phospho Ser529) antibody, Genetex, GTX55128

RELA (pS529) Antibody, Abbexa, abx000267

RELA (pS529) Antibody is a Rabbit Polyclonal antibody against RELA (pS529). NF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF-kappa-B moves to the nucleus and activates transcription of specific genes. NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with the product of this gene, RELA. Four transcript variants encoding different isoforms have been found for this gene.

Transcription Factor p65 Phospho-Thr505 (RELA pT505) Antibody, Abbexa, abx333292

RELA (pT505) Antibody is a Rabbit Polyclonal against RELA (pT505).

Transcription Factor p65 / NFKB3 (RELA) Antibody, Abbexa, abx031232

NFKB1 (MIM 164011) or NFKB2 (MIM 164012) is bound to REL (MIM 164910), RELA, or RELB (MIM 604758) to form the NFKB complex. The p50 (NFKB1) /p65 (RELA) heterodimer is the most abundant form of NFKB. The NFKB complex is inhibited by I-kappa-B proteins (NFKBIA, MIM 164008 or NFKBIB, MIM 604495), which inactivate NFKB by trapping it in the cytoplasm. Phosphorylation of serine residues on the I-kappa-B proteins by kinases (IKBKA, MIM 600664, or IKBKB, MIM 603258) marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NFKB complex. Activated NFKB complex translocates into the nucleus and binds DNA at kappa-B-binding motifs such as 5-prime GGGRNNYYCC 3-prime or 5-prime HGGARNYYCC 3-prime (where H is A, C, or T; R is an A or G purine; and Y is a C or T pyrimidine).