Search results for Erk1/2
Mitogen-Activated Protein Kinase 1 and 3 / ERK1/2 (MAPK1/MAPK3) Antibody, Abbexa, abx011157
Mitogen-activated protein kinases (MAPKs) are a widely conserved family of serine/threonine protein kinases involved in many cellular programs such as cell proliferation, differentiation, motility, and death. The p44/42 MAPK (Erk1/2) signaling pathway can be activated in response to a diverse range of extracellular stimuli including mitogens, growth factors, and cytokines and is an important target in the diagnosis and treatment of cancer. Upon stimulation, a sequential three-part protein kinase cascade is initiated, consisting of a MAP kinase kinase kinase (MAPKKK or MAP3K), a MAP kinase kinase (MAPKK or MAP2K), and a MAP kinase (MAPK). Multiple p44/42 MAP3Ks have been identified, including members of the Raf family as well as Mos and Tpl2/Cot. MEK1 and MEK2 are the primary MAPKKs in this pathway. MEK1 and MEK2 activate p44 and p42 through phosphorylation of activation loop residues Thr202/Tyr204 and Thr185/Tyr187, respectively. Several downstream targets of p44/42 have been identified, including p90RSK and the transcription factor Elk-1. p44/42 are negatively regulated by a family of dual-specificity (Thr/Tyr) MAPK phosphatases, known as DUSPs or MKPs, along with MEK inhibitors such as U0126 and PD98059.
Host
Mouse
Reactivity
Human, Mouse
Applications
ELISA, WB, IHC, FCM
Conjugation
Unconjugated
Mitogen-Activated Protein Kinase 1 and 3 / ERK1/2 (MAPK1/MAPK3) Antibody, Abbexa, abx327067
MAPK1/MAPK3 Antibody is a Rabbit Polyclonal against MAPK1/MAPK3.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB
Conjugation
Unconjugated
Mitogen-Activated Protein Kinase 1 and 3 / ERK1/2 (MAPK1/MAPK3) Antibody, Abbexa, abx013071
Rabbit polyclonal antibody against p44/42 MAPK protein. Immunogen region is C-terminal.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
Mitogen-Activated Protein Kinase 1 and 3 / ERK1/2 (MAPK1/MAPK3) Antibody, Abbexa, abx012726
Rabbit polyclonal antibody against MAPK1/3 protein. Immunogen region is Internal. Specificity is as follows for the reactive species: H:Y205/222, M:Y203/223, R:Y203/223.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
WB
Conjugation
Unconjugated
Mitogen-Activated Protein Kinase 1 and 3 / ERK1/2 (MAPK1/MAPK3) Antibody, Abbexa, abx012998
Rabbit polyclonal antibody against MAPK1/3 protein. Immunogen region is Internal.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
WB
Conjugation
Unconjugated
Mitogen-Activated Protein Kinase 1 and 3 / ERK1/2 (MAPK1/MAPK3) Antibody, Abbexa, abx232847
ERK1/2 Antibody is a Mouse Monoclonal against ERK1/2.
Host
Mouse
Reactivity
Human, Mouse
Applications
ELISA, WB, IHC, IF/ICC
Conjugation
Unconjugated
Mitogen-Activated Protein Kinase 1 and 3 / ERK1/2 (MAPK1/MAPK3) Antibody (ATTO390), Abbexa, abx447538
Erk1/2 Antibody (ATTO390) is a Rabbit Polyclonal against ERK1.
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Sheep, Chicken, Drosophila, Frog
Applications
WB, IHC, IF/ICC, FCM
Conjugation
ATTO390
Mitogen-Activated Protein Kinase 1 and 3 / ERK1/2 (MAPK1/MAPK3) Antibody (APC), Abbexa, abx447547
Erk1/2 Antibody (APC) is a Rabbit Polyclonal against ERK1.
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Sheep, Chicken, Drosophila, Frog
Applications
WB, IHC, IF/ICC, FCM
Conjugation
APC
Mitogen-Activated Protein Kinase 1 and 3 / ERK1/2 (MAPK1/MAPK3) Antibody (PerCP), Abbexa, abx447552
Erk1/2 Antibody (PerCP) is a Rabbit Polyclonal against ERK1.
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Sheep, Chicken, Drosophila, Frog
Applications
WB, IHC, IF/ICC, FCM
Conjugation
PerCP
Mitogen-Activated Protein Kinase 1 and 3 / ERK1/2 (MAPK1/MAPK3) Antibody (HRP), Abbexa, abx447550
Erk1/2 Antibody (HRP) is a Rabbit Polyclonal against ERK1.
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Sheep, Chicken, Drosophila, Frog
Applications
WB, IHC, IF/ICC, FCM
Conjugation
HRP
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