Search results for LGALS3

Lectin-Galactoside Binding Soluble 3 (LGALS3) Antibody, Abbexa, abx001250

LGALS3 Antibody is a Rabbit Polyclonal antibody against LGALS3. Galectins are a family of soluble b-galactoside-binding animal lectins that modulate cell-to-cell adhesion and cell-to-extracellular matrix (ECM) inter- actions and play a role in tumor progression, pre-mRNA splicing and apop-tosis. The galectin-3 protein, also known as Mac-2, hMac-2, GALBP, CBP35 or LGALS3, contains a single carbohydrate binding domain, which binds galactose-containing glycoconjugates. Galectin-3 is expressed in colonic and intestinal epithelium, inflammatory macrophages, papillary and follicular carcinomas, neoplastic astrocytes and some B and T lymphocytes. Upregulated expression of galectin-3 is involved in cancer progression and metastasis. Galectin-3 mediates the endocytosis of ∫1 Integrins in a lactose-dependent manner and is associated with thyroid malignancy and Crohn’s disease. It may also be used as a marker for diagnosing cases involving Hurthle cell adenomas and carcinomas.

Lectin-Galactoside Binding Soluble 3 (LGALS3) Antibody, Abbexa, abx323537

LGALS3 Antibody is a Rabbit Polyclonal against LGALS3.

Lectin-Galactoside Binding Soluble 3 (LGALS3) Antibody, Abbexa, abx027562

This gene encodes a member of the galectin family of carbohydrate binding proteins. Members of this protein family have an affinity for beta-galactosides. The encoded protein is characterized by an N-terminal proline-rich tandem repeat domain and a single C-terminal carbohydrate recognition domain. This protein can self-associate through the N-terminal domain allowing it to bind to multivalent saccharide ligands. This protein localizes to the extracellular matrix, the cytoplasm and the nucleus. This protein plays a role in numerous cellular functions including apoptosis, innate immunity, cell adhesion and T-cell regulation. Alternate splicing results in multiple transcript variants.

Anti-Mouse LGALS3/Galectin-3 Polyclonal Antibody, AntibodySystem, PMD27101

[KO Validated] Galectin 3/LGALS3 Rabbit pAb- ABclonal, ABclonal, A13506