Search results for CD274

CD274 Primary Antibody, ProMab, 31027

This gene encodes an immune inhibitory receptor ligand that is expressed by hematopoietic and non-hematopoietic cells, such as T cells and B cells and various types of tumor cells. The encoded protein is a type I transmembrane protein that has immunoglobulin V-like and C-like domains. Interaction of this ligand with its receptor inhibits T-cell activation and cytokine production. During infection or inflammation of normal tissue, this interaction is important for preventing autoimmunity by maintaining homeostasis of the immune response. In tumor microenvironments, this interaction provides an immune escape for tumor cells through cytotoxic T-cell inactivation. Expression of this gene in tumor cells is considered to be prognostic in many types of human malignancies, including colon cancer and renal cell carcinoma. Alternative splicing results in multiple transcript variants.

CD274 Primary Antibody, ProMab, 31530

This gene encodes an immune inhibitory receptor ligand that is expressed by hematopoietic and non-hematopoietic cells, such as T cells and B cells and various types of tumor cells. The encoded protein is a type I transmembrane protein that has immunoglobulin V-like and C-like domains. Interaction of this ligand with its receptor inhibits T-cell activation and cytokine production. During infection or inflammation of normal tissue, this interaction is important for preventing autoimmunity by maintaining homeostasis of the immune response. In tumor microenvironments, this interaction provides an immune escape for tumor cells through cytotoxic T-cell inactivation. Expression of this gene in tumor cells is considered to be prognostic in many types of human malignancies, including colon cancer and renal cell carcinoma. Alternative splicing results in multiple transcript variants.

Anti-Hu CD274 Purified, Covalab, Ref 122782

Anti-Hu CD274 APC, Covalab, Ref 122784

Anti-Hu CD274 FITC, Covalab, Ref 122785

Anti-Hu CD274 PE, Covalab, Ref 122786

Anti-Hu CD274 Purified, Covalab, Ref 00122782

Anti-Hu CD274 APC, Covalab, Ref 00122784

Anti-Hu CD274 FITC, Covalab, Ref 00122785

Anti-Hu CD274 PE, Covalab, Ref 00122786