Search results for Rb

Rb (pS811) Antibody, Abbexa, abx031911

Retinoblastoma (RB) is an embryonic malignant neoplasm of retinal origin. It almost always presents in early childhood and is often bilateral. Spontaneous regression occurs in some cases.

Rb (pS249) Antibody, Abbexa, abx031906

RB1 likely acts as a regulator of other genes. It forms a complex with adenovirus E1A and with SV40 large T antigen, acts as a tumor suppressor, and may bind and modulate functionally certain cellular proteins with which T and E1A compete for pocket binding. RB1 is a potent inhibitor of E2F-mediated trans-activation, and also recruits and targets histone methyltransferase SUV39H1 leading to epigenetic transcriptional repression. This protein inhibits the intrinsic kinase activity of TAF1. Defects in RB1 are the cause of childhood cancer retinoblastoma (RB), a congenital malignant tumor that arises from the nuclear layers of the retina. Defects in RB1 are also a cause of bladder cancer and osteogenic sarcoma.

Purified anti-Rb Phospho (Ser795) Antibody, Rb Phospho Ser795, A24001E, BioLegend, 640451

Purified anti-Rb Phospho (Ser795) Antibody, Rb Phospho Ser795, A24001E, BioLegend, 640452

PE anti-Rb Phospho (Ser795) Antibody, Rb Phospho Ser795, A24001E, BioLegend, 640455

PE anti-Rb Phospho (Ser795) Antibody, Rb Phospho Ser795, A24001E, BioLegend, 640456

Anti-RB-1 antibody, Abcam, AB224426

Anti-Rb antibody [EPR17512], Abcam, AB181616

Product Specifications Anti-Rb antibody [EPR17512] (ab181616) was developed by Abcam using patented rabbit monoclonal antibody technology and is validated for use in Flow Cyt (Intra), ICC/IF, IHC-P, IP, WB in african green monkey, human, mouse samples. Anti-Rb antibody [EPR17512] (ab181616) specifically detects Rb (UniProt ID: P13405; Molecular weight: 105kDa) and is sold in a convenient trial size to enable initial testing (20 µL) and larger sizes for subsequent scaling up experiments (100 µL and 1 mL). Quality and Validation Abcam's high quality manufacturing and validation processes ensure Anti-Rb antibody [EPR17512] (ab181616) has high sensitivity and specificity alongside high lot-to-lot consistency and reproducibility. The specificity of Anti-Rb antibody [EPR17512] (ab181616) has been confirmed by testing in knockout samples. Anti-Rb antibody [EPR17512] (ab181616) has been cited over 83 times in peer reviewed journals and is trusted by the scientific community. Related Products Antibody clone EPR17512 is also available pre-conjugated to a variety of labels for your convenience - Alexa Fluor® 647, Alexa Fluor® 594, Alexa Fluor® 488, Alexa Fluor® 555 ( ab300158 , ab300670 , ab300671 , ab300672 ). Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents . What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies .

Anti-Rb antibody [SPM353], Abcam, AB218505

RB Rabbit pAb- ABclonal, ABclonal, A0003SP