Search results for 14-3-3

14-3-3 Protein Epsilon (YWHAE) Antibody, Abbexa, abx000981

YWHAE Antibody is a Rabbit Polyclonal antibody against YWHAE. This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 100% identical to the mouse ortholog. It interacts with CDC25 phosphatases, RAF1 and IRS1 proteins, suggesting its role in diverse biochemical activities related to signal transduction, such as cell division and regulation of insulin sensitivity. It has also been implicated in the pathogenesis of small cell lung cancer. Two transcript variants, one protein-coding and the other non-protein-coding, have been found for this gene.

14-3-3 Beta/alpha (YWHAB) Antibody, Abbexa, abx019001

14-3-3 beta/alpha Antibody is a Rabbit Polyclonal antibody against Human, Mouse and Rat.

14-3-3 Protein Gamma (YWHAG) Antibody, Abbexa, abx013881

Rabbit polyclonal antibody against 14-3-3 gamma protein. Immunogen region is Internal.

14-3-3 Protein Epsilon (YWHAE) Antibody, Abbexa, abx318490

YWHAE Antibody is a Rabbit Polyclonal against YWHAE.

14-3-3 Protein Sigma (SFN) Antibody, Abbexa, abx030571

This product is currently in development. The lead time for this product may be several months. Please contact us at [email protected] for an updated lead time before purchasing this product. This product is currently in development. The lead time for this product may be several months. Please contact us at [email protected] for an updated lead time before purchasing this product. Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathway. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. When bound to KRT17, regulates protein synthesis and epithelial cell growth by stimulating Akt/mTOR pathway (By similarity). p53-regulated inhibitor of G2/M progression.

14-3-3 Protein Sigma (SFN) Antibody, Abbexa, abx455152

14-3-3 Protein Sigma (SFN) Antibody is a Rabbit polyclonal antibody for the detection of Human 14-3-3 Protein Sigma (SFN).

14-3-3 Protein Theta (YWHAQ) Antibody, Abbexa, abx137294

14-3-3 Protein Theta (YWHAQ) Antibody is a Mouse Monoclonal antibody against 14-3-3 Protein Theta (YWHAQ).

14-3-3 Theta Rabbit pAb- ABclonal, ABclonal, A2563

14-3-3 Protein Sigma (SFN) Antibody, Abbexa, abx032680

SFN Antibody is a Rabbit Polyclonal antibody against SFN.

14-3-3 Protein Sigma (SFN) Antibody, Abbexa, abx218542

14-3-3 Protein Sigma (SFN) Antibody is a Rabbit Polyclonal antibody for the detection of SFN. 14-3-3 proteins regulate many cellular processes relevant to cancer biology, notably apoptosis, mitogenic signaling and cell-cycle checkpoints. Seven isoforms, denoted 14-3-3 b, g, e, z, h, q and s, comprise this family of signaling intermediates. 14-3-3 s, also known as SFN, stratifin, HME1 or YWHAS, is a secreted adaptor protein that is involved in regulating both general and specific signaling pathways. Expressed predominately in stratified squamous keratinising epithelium, 14-3-3 s is able to bind and modify the activity of a large number of proteins, such as KRT17 (Keratin 17), through recognition of a phosphothreonine or phosphoserine motif. When bound to Keratin 17, for example, 14-3-3 s acts to stimulate the Akt/mTOR signaling pathway by upregulating protein synthesis and cell growth. 14-3-3 s also functions to positively mediate IGF-I-induced cell cycle progression and can bind to a variety of translation initiation factors, thus controlling mitotic translation. In response to tumor growth, 14-3-3 s positively regulates the tumor suppressor p53 and increases the rate of p53-regulated inhibition of G2/M cell cycle progression. Multiple isoforms of 14-3-3 s exist due to alternative splicing events.