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Source / PurificationMonoclonal antibody is produced by immunizing animals with synthetic phosphopeptides corresponding to residues surrounding Tyr1068 of human EGFR

(1)

Tyr1221/1222 of human ErbB2

(1)

or to Tyr1289 of human HER3/ErbB3. Monoclonal antibody to EGFR is produced by immunizing animals with a synthetic GST-fusion protein corresponding to residues containing the cytoplasmic domain of human EGF receptor.

(1)

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Search results for erbb2

Showing 1 – 10 of350products

ID: BAB065469233

Her2 / ErbB2 antibody [6C2], Genetex, GTX82764

Host

Mouse

Reactivity

Human

Applications

WB ICC/IF IHC-P FCM ELISA

Conjugation

Unconjugated

Compare

Suppliers

ID: BAB545052946

M ERBB2 (pY1140) Antibody, Abbexa, abx032151

This gene encodes a member of the epidermal growth factor (EGF) receptor family of receptor tyrosine kinases. This protein has no ligand binding domain of its own and therefore cannot bind growth factors. However, it does bind tightly to other ligand-bound EGF receptor family members to form a heterodimer, stabilizing ligand binding and enhancing kinase-mediated activation of downstream signalling pathways, such as those involving mitogen-activated protein kinase and phosphatidylinositol-3 kinase. Allelic variations at amino acid positions 654 and 655 of isoform a (positions 624 and 625 of isoform b) have been reported, with the most common allele, Ile654/Ile655, shown here. Amplification and/or overexpression of this gene has been reported in numerous cancers, including breast and ovarian tumors. Alternative splicing results in several additional transcript variants, some encoding different isoforms and others that have not been fully characterized.

Host

Rabbit

Reactivity

Human, Mouse

Applications

ELISA, WB, DB

Conjugation

Unconjugated

Compare

Suppliers

ID: BAB361507297

rat ERBB2 (pT1168) Antibody, Abbexa, abx032260

Essential component of a neuregulin-receptor complex, although neuregulins do not interact with it alone. GP30 is a potential ligand for this receptor. Binds to the 5'-TCAAATTC-3' sequence in the MT-CO2 promoter and activates its transcription (By similarity).

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