Search results for tyrosine kinase

Showing 1 – 10 of509products
Leukocyte tyrosine kinase receptor (LTK) Antibody Brand Logo
ID: BAB799532117

Leukocyte tyrosine kinase receptor (LTK) Antibody, Abbexa, abx326229

LTK Antibody is a Rabbit Polyclonal against LTK.

Host

Rabbit

Reactivity

Human, Mouse

Applications

ELISA, WB, IHC, IF/ICC

Conjugation

Unconjugated

Leukocyte Tyrosine Kinase Receptor (LTK) Antibody Brand Logo
ID: BAB988775030

Leukocyte Tyrosine Kinase Receptor (LTK) Antibody, Abbexa, abx033582

Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The tyrosine kinase (TK) group is mainly involved in the regulation of cell-cell interactions such as differentiation, adhesion, motility and death. There are currently about 90 TK genes sequenced, 58 are of receptor protein TK (e.g. EGFR, EPH, FGFR, PDGFR, TRK, and VEGFR families), and 32 of cytosolic TK (e.g. ABL, FAK, JAK, and SRC families).

Host

Rabbit

Reactivity

Human

Applications

ELISA, WB

Conjugation

Unconjugated

Protein Tyrosine Kinase 6 (PTK6) Antibody Brand Logo
ID: BAB802930485

Protein Tyrosine Kinase 6 (PTK6) Antibody, Abbexa, abx128170

Protein Tyrosine Kinase 6 Antibody is a Rabbit Polyclonal against Protein Tyrosine Kinase 6.

Host

Rabbit

Reactivity

Human

Applications

WB, IHC, IF/ICC

Conjugation

Unconjugated

ALK Tyrosine Kinase Receptor (ALK) Antibody Brand Logo
ID: BAB511836484

ALK Tyrosine Kinase Receptor (ALK) Antibody, Abbexa, abx325369

ALK Antibody is a Rabbit Polyclonal against ALK.

Host

Rabbit

Reactivity

Human, Mouse

Applications

ELISA, WB

Conjugation

Unconjugated

Related To Receptor Tyrosine Kinase (RYK) Antibody Brand Logo
ID: BAB347380288

Related To Receptor Tyrosine Kinase (RYK) Antibody, Abbexa, abx129056

Related To Receptor Tyrosine Kinase Antibody is a Rabbit Polyclonal against Related To Receptor Tyrosine Kinase.

Host

Rabbit

Reactivity

Human

Applications

WB, IHC, IF/ICC

Conjugation

Unconjugated

Spleen Associated Tyrosine Kinase (SYK) Antibody Brand Logo
ID: BAB597505228

Spleen Associated Tyrosine Kinase (SYK) Antibody, Abbexa, abx326795

SYK Antibody is a Rabbit Polyclonal against SYK.

Host

Rabbit

Reactivity

Human, Mouse, Rat

Applications

ELISA, IHC, IF/ICC

Conjugation

Unconjugated

Megakaryocyte Associated Tyrosine Kinase (MATK) Antibody Brand Logo
ID: BAB311110350

Megakaryocyte Associated Tyrosine Kinase (MATK) Antibody, Abbexa, abx011115

MATK (megakaryocyte-associated tyrosine kinase), also known as CTK, this protein has amino acid sequence similarity to Csk tyrosine kinase and has the structural features of the CSK subfamily: SRC homology SH2 and SH3 domains, a catalytic domain, a unique N terminus, lack of myristylation signals, lack of a negative regulatory phosphorylation site, and lack of an autophosphorylation site. This protein is thought to play a significant role in the signal transduction of hematopoietic cells. It is able to phosphorylate and inactivate Src family kinases, and may play an inhibitory role in the control of T-cell proliferation. This protein might be involved in signaling in some cases of breast cancer.

Host

Mouse

Reactivity

Human

Applications

ELISA, WB, FCM

Conjugation

Unconjugated

Lemur Tyrosine Kinase 2 (LMTK2) Antibody Brand Logo
ID: BAB251727603

Lemur Tyrosine Kinase 2 (LMTK2) Antibody, Abbexa, abx033196

Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The tyrosine kinase (TK) group is mainly involved in the regulation of cell-cell interactions such as differentiation, adhesion, motility and death. There are currently about 90 TK genes sequenced, 58 are of receptor protein TK (e.g. EGFR, EPH, FGFR, PDGFR, TRK, and VEGFR families), and 32 of cytosolic TK (e.g. ABL, FAK, JAK, and SRC families).

Host

Rabbit

Reactivity

Human

Applications

ELISA, WB, IHC

Conjugation

Unconjugated

ALK Tyrosine Kinase Receptor (ALK) Antibody Brand Logo
ID: BAB710075077

ALK Tyrosine Kinase Receptor (ALK) Antibody, Abbexa, abx224449

ALK Antibody is a Mouse Monoclonal against ALK.

Host

Mouse

Reactivity

Human

Applications

ELISA, FCM

Conjugation

Unconjugated

Spleen Associated Tyrosine Kinase (SYK) Antibody Brand Logo
ID: BAB309288696

Spleen Associated Tyrosine Kinase (SYK) Antibody, Abbexa, abx011584

Syk is a cytoplasmic tyrosine kinase of the SYK family containing two SH2 domains. Plays a central role in the B cell receptor (BCR) response. An upstream activator of the PI3K, PLC gamma 2, and Rac/cdc42 pathways in the BCR response. Required for the sequential events of Fc gamma IIa receptor-mediated phagocytosis. Expression highest in murine spleen, heart, mammary gland and thymus. Two splice variant isoforms have been described.

Host

Mouse

Reactivity

Human

Applications

ELISA, WB

Conjugation

Unconjugated

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