Search results for IAP
Baculoviral IAP Repeat-Containing Protein 5 (BIRC5) Antibody, Abbexa, abx010443
Baculoviral IAP repeat-containing 5 (survivin). This gene is a member of the inhibitor of apoptosis (IAP) gene family, which encode negative regulatory proteins that prevent apoptotic cell death. IAP family members usually contain multiple baculovirus IAP repeat (BIR) domains, but this gene encodes proteins with only a single BIR domain. The encoded proteins also lack a C-terminus RING finger domain. Gene expression is high during fetal development and in most tumors yet low in adult tissues. Antisense transcripts are involved in the regulation of this gene's expression. At least four transcript variants encoding distinct isoforms have been found for this gene, but the full-length natures of only three of them have been determined.
Host
Mouse
Reactivity
Human
Applications
ELISA
Conjugation
Unconjugated
Baculoviral IAP Repeat-Containing Protein 5 (BIRC5) Antibody, Abbexa, abx100296
Monoclonal Antibody to Survivin (BIRC5).
Host
Mouse
Reactivity
Human
Applications
WB, IHC, IF/ICC
Conjugation
Unconjugated
Baculoviral IAP Repeat-Containing Protein 5 (BIRC5) Antibody, Abbexa, abx326820
BIRC5 Antibody is a Rabbit Polyclonal against BIRC5.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, IHC
Conjugation
Unconjugated
Baculoviral IAP Repeat-Containing Protein 5 (BIRC5) Antibody, Abbexa, abx011577
survivin is an apoptosis inhibitor that is expressed during the G2/M phase of the cell cycle. Associates with the microtubules of the mitotic spindle and any disruption results in the loss of apoptosis activity. May play a role in neoplasia. Inhibitor of caspase-3 and caspase-7. Two splice variant isoforms have been described.
Host
Mouse
Reactivity
Human
Applications
ELISA, WB, IHC, IF/ICC, FCM
Conjugation
Unconjugated
Baculoviral IAP Repeat-Containing Protein 2 (BIRC2) Antibody, Abbexa, abx000938
BIRC2 Antibody is a Rabbit Polyclonal antibody against BIRC2. The protein encoded by this gene is a member of a family of proteins that inhibits apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. This encoded protein inhibits apoptosis induced by serum deprivation and menadione, a potent inducer of free radicals. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Host
Rabbit
Reactivity
Human, Mouse
Applications
ELISA, WB
Conjugation
Unconjugated
Baculoviral IAP Repeat-Containing Protein 5 (BIRC5) Antibody, Abbexa, abx111181
Baculoviral Iap Repeat-Containing 5 Antibody is a Rabbit Polyclonal antibody against Baculoviral Iap Repeat-Containing 5.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
Baculoviral IAP Repeat Containing Protein 7 (BIRC7) Antibody, Abbexa, abx211305
BIRC7 Antibody is a Rabbit Polyclonal against BIRC7.
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB
Conjugation
Unconjugated
Baculoviral IAP Repeat Containing Protein 6 (BIRC6) Antibody, Abbexa, abx430330
BIRC6 Antibody is a Goat Polyclonal antibody against BIRC6.
Host
Goat
Reactivity
Applications
P-ELISA
Conjugation
Unconjugated
Baculoviral IAP Repeat-Containing Protein 2 (BIRC2) Antibody, Abbexa, abx321438
BIRC2 Antibody is a Rabbit Polyclonal against BIRC2.
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
Baculoviral IAP Repeat Containing Protein 7 (BIRC7) Antibody, Abbexa, abx004387
BIRC7 Antibody is a Rabbit Polyclonal antibody against BIRC7. This gene encodes a member of the inhibitor of apoptosis protein (IAP) family, and contains a single copy of a baculovirus IAP repeat (BIR) as well as a RING-type zinc finger domain. The BIR domain is essential for inhibitory activity and interacts with caspases, while the RING finger domain sometimes enhances antiapoptotic activity but does not inhibit apoptosis alone. Elevated levels of the encoded protein may be associated with cancer progression and play a role in chemotherapy sensitivity. Alternative splicing results in multiple transcript variants.
Host
Rabbit
Reactivity
Human, Mouse
Applications
ELISA, WB
Conjugation
Unconjugated
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