Search results for alpha-chain

GA-Binding Protein Alpha Chain (GABPA) Antibody, Abbexa, abx455865

GA-Binding Protein Alpha Chain (GABPA) Antibody is a Rabbit polyclonal antibody for the detection of Human GA-Binding Protein Alpha Chain (GABPA).

Human IgA, Alpha Chain specific antibody [Biotin], Covalab, Ref 00098406

Anti-Clusterin alpha chain antibody [EPR17539-95], Abcam, AB184100

Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents . What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies .

T Cell Receptor Alpha Chain Constant (TRAC) Antibody, Abbexa, abx415683

T Cell Receptor Alpha Chain Constant (TRAC) Antibody is a Mouse Monoclonal antibody against TCR ALPHA.

C4b-Binding Protein Alpha Chain (C4BPA) Antibody (FITC), Abbexa, abx273689

C4b-Binding Protein Alpha Chain (C4BPA) Antibody (FITC) is a Rabbit Polyclonal antibody conjugated to FITC against C4b-Binding Protein Alpha Chain (C4BPA).

Potassium-Transporting ATPase Alpha Chain 2 (ATP12A) Antibody, Abbexa, abx038054

Rabbit Polyclonal against the ATP12A protein.

C4b-Binding Protein Alpha Chain (C4BPA) Antibody (HRP), Abbexa, abx303257

C4b-Binding Protein Alpha Chain (C4BPA) Antibody (HRP) is a Rabbit Polyclonal against C4b-Binding Protein Alpha Chain (C4BPA) conjugated to HRP.

C3/C3b/iC3b (alpha chain), Human, clone 18.1, Hycult Biotech, HM2389

The complement system is a key part of our immune system, helping to fight infections and protect the body. It reacts quickly to germs, even before our main immune response kicks in. This system is made up of many proteins and receptors, such as C3, C3b, and iC3b, which are found in the blood, tissues, and different body fluids. Exploring the Three Pathways of Complement Activation The complement system can be activated in three different ways. First, the classical pathway starts when immune complexes are present. Second, the lectin pathway begins with lectins attached to surfaces. Third, the alternative pathway (AP) is triggered on unprotected surfaces. All these pathways create a special enzyme called C3 convertase. This enzyme is important because it cuts the main protein, C3, into a smaller piece known as C3b. The C3 and C5 convertases are enzymatic complexes that initiate and amplify the activity of the complement pathways, leading to the generation of the cytolytic membrane attack complex (MAC). The synthesis of C3, including its forms C3b and iC3b, is tissue-specific and modulated in response to various stimulatory agents. Upon cleavage by C3 convertase, the anaphylotoxin C3a and the activating fragment C3b are formed. C3b, when bound to the cell surface, initiates the terminal pathway of complement by forming the C5 convertase. Understanding C3, C3b, and iC3b: Crucial Components of Immune Defense C3, with a molecular weight of approximately 185kDa, is the most abundant protein in the complement system, featuring serum protein levels of about 1.3 mg/ml. Primarily produced by the liver, C3, as well as its derivatives C3b and iC3b, are also synthesized in macrophages, neutrophils, endothelial, and epithelial cells. Due to its high levels in circulation and low biological reactivity, C3/C3b/iC3b acts swiftly and potently in response to dangers, such as pathogen encounters. However, defects in C3/C3b/iC3b can be detrimental, leading to recurrent infections or autoimmune diseases. C3 deficiency is uncommon, but it does happen. This deficiency affects how well C3b and iC3b work. It leads to frequent infections and problems with the development of immune cells. Polymorphisms in C3 have been associated with conditions like age-related macular degeneration (AMD) and atypical hemolytic uremic syndrome (aHUS). Beyond pathogen clearance, C3/C3b/iC3b plays a vital role in the removal of circulating immune complexes, aiding the phagocytic capacity of macrophages. Malfunctions in this system can lead to autoimmune diseases and complement deposition in tissues. Not sure which C3 antibody to use? With numerous options available, it is essential to select the right C3 antibody to ensure the success of your research. We designed a guide to assist you in making an informed decision: Go to our C3 researcher’s guide and choose the right antibody

Mouse Spectrin alpha chain, brain (SPTAN1) ELISA Kit, Abbkine, KTE70249

• Do not mix components from different kit lots or use reagents beyond the kit expiration date.• Allow all reagents to warm to room temperature for at least 30 minutes before opening.• Pre-rinse the pipet tip with reagent, use fresh pipet tips for each sample, standard and reagent to avoid contamination. • Unused wells must be kept desiccated at 4 °C in the sealed bag provided.• Mix Thoroughly is very important for the result. It is recommended using low frequency oscillator or slight hand shaking every 10 minutes.• It is recommended that all samples and standards be assayed in duplicate or triplicate.

Spectrin Alpha Chain, Non-Erythrocytic 1 (SPTAN1) Antibody, Abbexa, abx456038

Spectrin Alpha Chain, Non-Erythrocytic 1 (SPTAN1) Antibody is a Rabbit polyclonal antibody for the detection of Human Spectrin Alpha Chain, Non-Erythrocytic 1 (SPTAN1).