Search results for 387

Spark UV™ 387 anti-mouse F4/80 (Flexi-Fluor™) Antibody, F4/80, W20065D, BioLegend, 285504

Spark UV™ 387 anti-human CD206 (MMR) (Flexi-Fluor™) Antibody, CD206, 15-2, BioLegend, 285507

The 15-2 antibody blocks the interaction of MMR with its ligand, and inhibits mannose receptor-mediated degradation of t-PA by macrophages. Additional reported applications of this antibody (for the relevant formats) include: Western blotting1, blocking of ligand binding1,2, immunofluorescence3, and immunohistochemical staining of acetone-fixed frozen tissue sections1. The Utra-LEAF™ purified antibody (Endotoxin < 0.01 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. No. 321149 and 321150).

Spark UV™ 387 anti-mouse CD117 (c-kit) (Flexi-Fluor™)Antibody, CD117, 2B8, BioLegend, 285508

Additional reported applications (for the relevant formats) include: immunoprecipitation1, immunohistochemistry of acetone fixed frozen sections2, and spatial biology (IBEX)5,6. The 2B8 antibody does not block c-Kit activity.

Spark UV™ 387 anti-mouse CD127 (IL-7Rα) (Flexi-Fluor™) Antibody, CD127, A7R34, BioLegend, 285510

Clone A7R34 is able to completely block the binding of clone S18006K to IL-7Rα. It does not block SB/199.

Spark UV™ 387 anti-human CD107a (LAMP-1) (Flexi-Fluor™) Antibody, CD107a, H4A3, BioLegend, 285495

Additional reported applications (for the relevant formats) include: Western blotting8, immunohistochemical staining2, immunofluorescence5,7, and immunoprecipitation5.This antibody is specific to human LAMP-1. Positive control: Hela cells; LAMP-1 molecular weight appears to be at ~110 kDa on the gel due to high glycosylation.

Spark UV™ 387 anti-mouse I-A/I-E Antibody, I-A/I-E, M5/114.15.2, BioLegend, 107669

The M5/114.15.2 antibody reacts with a polymorphic determinant shared by the I-Ab, I-Ad, I-Aq, I-Ed, and I-EkMHC class II alloantigens from mice carrying H-2p,r,q,b,d,uhaplotypes. Clone M5/114.15.2 however does not react wtih I-Af, I-Ak, or I-AsMHC class II alloantigens.1Additional reported applications (for the relevant formats) include: immunoprecipitation1, immunohistochemistry of frozen sections2,3,6,in vitroandin vivoblocking of antigen presentation or ligand binding4-7, and spatial biology (IBEX)17,18. The Ultra-LEAF™ purified antibody (Endotoxin < 0.01 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. Nos. 107655 & 107656).

Spark UV™ 387 anti-mouse I-A/I-E Antibody, I-A/I-E, M5/114.15.2, BioLegend, 107670

The M5/114.15.2 antibody reacts with a polymorphic determinant shared by the I-Ab, I-Ad, I-Aq, I-Ed, and I-EkMHC class II alloantigens from mice carrying H-2p,r,q,b,d,uhaplotypes. Clone M5/114.15.2 however does not react wtih I-Af, I-Ak, or I-AsMHC class II alloantigens.1Additional reported applications (for the relevant formats) include: immunoprecipitation1, immunohistochemistry of frozen sections2,3,6,in vitroandin vivoblocking of antigen presentation or ligand binding4-7, and spatial biology (IBEX)17,18. The Ultra-LEAF™ purified antibody (Endotoxin < 0.01 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. Nos. 107655 & 107656).

Spark UV™ 387 anti-mouse TCR β chain (Flexi-Fluor™) Antibody, TCR β chain, H57-597, BioLegend, 285496

H57-597 is a hamster mAb directed to an epitope of the C region of TCR ß chain12. The H57-597 antibody does not cross-react with ?/d TCR-bearing T cells. Immobilized or soluble H57-597 antibody can activate a/ß TCR-bearing T cells. Additional reported applications (for the relevant formats) for this antibody include: immunoprecipitation2,in vitrostimulation2,3,in vivodepletion4-6, and immunohistochemical staining of acetone-fixed frozen sections7,8,9. The Ultra-LEAF™ purified antibody (Endotoxin <0.01 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. No. 109253-109258).

Spark UV™ 387 anti-mouse TER-119/Erythroid Cells (Flexi-Fluor™) Antibody, TER-119, TER-119, BioLegend, 285503

The TER-119 antibody is useful for distinguishing erythrocytes and cells in the erythroid lineage. Additional reported applications (for the relevant formats) include: immunoprecipitation1, Western blotting1, complement-mediated cytotoxicity3, and immunohistochemical staining of acetone-fixed frozen sections and formalin-fixed paraffin-embedded sections. Ultra-LEAF™ purified antibody (Endotoxin < 0.01 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. No. 116253-116258).

Spark UV™ 387 anti-mouse Ly-6A/E (Sca-1) (Flexi-Fluor™) Antibody, Ly-6A/E, D7, BioLegend, 285511

The D7 antibody has been reported to induce T cell activation and inhibit TCR-induced IL-2 production. Additional reported applications (for the relevant formats) include: Western blotting1,2, immunoprecipitation1,in vitrolymphocyte activation3-6, induction of redirected lysis7, induction of T cell inhibitory signalling8, immunofluorescence9, and immunohistochemical staining of acetone-fixed frozen sections13and Bouin-fixed, paraffin-embedded samples9.The two Sca-1 recognizing clones D7 andE13-161.7have been shown to bind distinct epitopes due to the inability of D7 to block the binding of E13-161.7.14