Search results for 7157

p53 (phospho Ser46) antibody [HL3795], Genetex, GTX642014

Cellular Tumor Antigen p53 (TP53) Antibody, Abbexa, abx032763

Tumor protein p53, a nuclear protein, plays an essential role in the regulation of cell cycle, specifically in the transition from G0 to G1. It is found in very low levels in normal cells, however, in a variety of transformed cell lines, it is expressed in high amounts, and believed to contribute to transformation and malignancy. p53 is a DNA-binding protein containing DNA-binding, oligomerization and transcription activation domains. It is postulated to bind as a tetramer to a p53-binding site and activate expression of downstream genes that inhibit growth and/or invasion, and thus function as a tumor suppressor. Mutants of p53 that frequently occur in a number of different human cancers fail to bind the consensus DNA binding site, and hence cause the loss of tumor suppressor activity. Alterations of the TP53 gene occur not only as somatic mutations in human malignancies, but also as germline mutations in some cancer-prone families with Li-Fraumeni syndrome.

p53 (phospho Ser15) antibody, Genetex, GTX132995

p53 (phospho Ser46) antibody, Genetex, GTX132996

p53 (phospho Ser33) antibody, Genetex, GTX133902

p53 (phospho Ser6) antibody, Genetex, GTX133905

Cellular Tumor Antigen P53 (TP53) Antibody, Abbexa, abx422675

Cellular Tumor Antigen P53 (TP53) Antibody is a Mouse monoclonal against Cellular Tumor Antigen P53 (TP53).

Cellular Tumor Antigen p53 Phospho-Ser9 (TP53 pS9) Antibody, Abbexa, abx031898

Tumor protein p53, a nuclear protein, plays an essential role in the regulation of cell cycle, specifically in the transition from G0 to G1. It is found in very low levels in normal cells, however, in a variety of transformed cell lines, it is expressed in high amounts, and believed to contribute to transformation and malignancy. p53 is a DNA-binding protein containing DNA-binding, oligomerization and transcription activation domains. It is postulated to bind as a tetramer to a p53-binding site and activate expression of downstream genes that inhibit growth and/or invasion, and thus function as a tumor suppressor. Mutants of p53 that frequently occur in a number of different human cancers fail to bind the consensus DNA binding site, and hence cause the loss of tumor suppressor activity. Alterations of the TP53 gene occur not only as somatic mutations in human malignancies, but also as germline mutations in some cancer-prone families with Li-Fraumeni syndrome.

Cellular Tumor Antigen p53 (TP53) Antibody, Abbexa, abx325017

TP53 Antibody is a Rabbit Polyclonal against TP53.

Cellular Tumor Antigen p53 Acetyl-Lys381 (TP53 AcK381) Antibody, Abbexa, abx326734

Acetyl-TP53 (K381) Antibody is a Rabbit Polyclonal against Acetyl-TP53 (K381).