Search results for A-RAF

Raf Proto-Oncogene Serine/Threonine Protein Kinase (RAF1) Antibody, Abbexa, abx218161

Raf Proto-Oncogene Serine/Threonine Protein Kinase (RAF1) Antibody is a Rabbit Polyclonal antibody for the detection of RAF1. Serine/threonine-protein kinase that acts as a regulatory link between the membrane-associated Ras GTPases and the MAPK/ERK cascade, and this critical regulatory link functions as a switch determining cell fate decisions including proliferation, differentiation, apoptosis, survival and oncogenic transformation. RAF1 activation initiates a mitogen-activated protein kinase (MAPK) cascade that comprises a sequential phosphorylation of the dual-specific MAPK kinases (MAP2K1/MEK1 and MAP2K2/MEK2) and the extracellular signal-regulated kinases (MAPK3/ERK1 and MAPK1/ERK2). The phosphorylated form of RAF1 (on residues Ser-338 and Ser-339, by PAK1) phosphorylates BAD/Bcl2-antagonist of cell death at 'Ser-75'. Phosphorylates adenylyl cyclases: ADCY2, ADCY5 and ADCY6, resulting in their activation. Phosphorylates PPP1R12A resulting in inhibition of the phosphatase activity. Phosphorylates TNNT2/cardiac muscle troponin T. Can promote NF-kB activation and inhibit signal transducers involved in motility (ROCK2), apoptosis (MAP3K5/ASK1 and STK3/MST2), proliferation and angiogenesis (RB1). Can protect cells from apoptosis also by translocating to the mitochondria where it binds BCL2 and displaces BAD/Bcl2-antagonist of cell death. Regulates Rho signaling and migration, and is required for normal wound healing. Plays a role in the oncogenic transformation of epithelial cells via repression of the TJ protein, occludin (OCLN) by inducing the up-regulation of a transcriptional repressor SNAI2/SLUG, which induces down-regulation of OCLN. Restricts caspase activation in response to selected stimuli, notably Fas stimulation, pathogen-mediated macrophage apoptosis, and erythroid differentiation.

Raf Proto-Oncogene Serine/Threonine Protein Kinase (RAF1) Antibody, Abbexa, abx328547

RAF1 Antibody is a Rabbit Polyclonal against RAF1.

Rat Serine/Threonine-Protein Kinase A-Raf (ARAF) ELISA Kit, Abbexa, abx502230

Rat Serine/Threonine-Protein Kinase A-Raf (ARAF) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Rat Serine/threonine-protein kinase A-Raf concentrations in serum, plasma, tissue homogenates, cell culture supernatants and other biological fluids.

Raf Proto-Oncogene Serine/Threonine Protein Kinase (RAF1) Antibody, Abbexa, abx305042

RAF1 Antibody is a Rabbit Polyclonal against RAF1.

Raf Proto-Oncogene Serine/Threonine Protein Kinase (RAF1) Antibody, Abbexa, abx323235

RAF1 Antibody is a Rabbit Polyclonal against RAF1.

Raf Proto-Oncogene Serine/Threonine Protein Kinase (RAF1) Antibody, Abbexa, abx122947

Rabbit Polyclonal against the RAF1 protein.

Human Serine/Threonine-Protein Kinase A-Raf (ARAF) ELISA Kit, Abbexa, abx385807

Human Serine/Threonine-Protein Kinase A-Raf (ARAF) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human V-Raf Murine Sarcoma 3611 Viral Oncogene Homolog (ARAF) concentrations in tissue homogenates, cell lysates and other biological fluids.

Raf Proto-Oncogene Serine/Threonine Protein Kinase (RAF1) Antibody, Abbexa, abx329894

RAF1 Antibody is a Rabbit Polyclonal against RAF1.

Anti-Human BRAF/B-Raf (V600E) Antibody (SAA2181) (HB617033), abinScience, HB617033

Serine/Threonine-Protein Kinase A-Raf Phospho-Ser299 (ARAF pS299) Antibody, Abbexa, abx326606

ARAF (pS299) Antibody is a Rabbit Polyclonal against ARAF (pS299).