Search results for ERBB3
V-Erb B2 Erythroblastic Leukemia Viral Oncogene Homolog 3 (ERBB3) Antibody, Abbexa, abx015711
ERBB3, v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian).It is a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases.This membrane-bound protein has a neuregulin binding domain but not an active kinase domain.It therefore can bind this ligand but not convey the signal into the cell through protein phosphorylation.However, it does form heterodimers with other EGF receptor family members which do have kinase activity.Heterodimerization leads to the activation of pathways which lead to cell proliferation or differentiation.Amplification of this gene and/or overexpression of its protein have been reported in numerous cancers, including prostate, bladder, and breast tumors.Alternate transcriptional splice variants encoding different isoforms have been characterized.One isoform lacks the intermembrane region and is secreted outside the cell.This form acts to modulate the activity of the membrane-bound form.Additional splice variants have also been reported, but they have not been thoroughly characterized.
Host
Mouse
Reactivity
Human
Applications
ELISA, IF/ICC
Conjugation
Unconjugated
V-Erb B2 Erythroblastic Leukemia Viral Oncogene Homolog 3 (ERBB3) Antibody, Abbexa, abx324565
ERBB3 Antibody is a Rabbit Polyclonal against ERBB3.
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
V-Erb B2 Erythroblastic Leukemia Viral Oncogene Homolog 3 (ERBB3) Antibody, Abbexa, abx015743
ERBB3: v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian).This gene encodes a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases.This membrane-bound protein has a neuregulin binding domain but not an active kinase domain.It therefore can bind this ligand but not convey the signal into the cell through protein phosphorylation.However, it does form heterodimers with other EGF receptor family members which do have kinase activity.Heterodimerization leads to the activation of pathways which lead to cell proliferation or differentiation.Amplification of this gene and/or overexpression of its protein have been reported in numerous cancers, including prostate, bladder, and breast tumors.Alternate transcriptional splice variants encoding different isoforms have been characterized.One isoform lacks the intermembrane region and is secreted outside the cell.This form acts to modulate the activity of the membrane-bound form.Additional splice variants have also been reported, but they have not been thoroughly characterized.
Host
Mouse
Reactivity
Human
Applications
ELISA
Conjugation
Unconjugated
V-Erb B2 Erythroblastic Leukemia Viral Oncogene Homolog 3 (ErbB3) Antibody, Abbexa, abx129832
V-Erb B2 Erythroblastic Leukemia Viral Oncogene Homolog 3 Antibody is a Rabbit Polyclonal against V-Erb B2 Erythroblastic Leukemia Viral Oncogene Homolog 3.
Host
Rabbit
Reactivity
Mouse
Applications
WB, IHC, IF/ICC
Conjugation
Unconjugated
V-Erb B2 Erythroblastic Leukemia Viral Oncogene Homolog 3 (ERBB3) Antibody, Abbexa, abx033547
ErbB3, a member of the EGF receptor family, binds and is activated by neuregulins and NTAK. It potentially forms a heterodimer with each of the other ERBB receptors. This protein is predominantly expressed in epithelial tissues and brain. The cytoplasmic part of the receptor may interact with the SH2 or SH3 domains of many signal-transducing proteins. Ligand-binding may increase phosphorylation on tyrosine residues and promote its association with the p85 subunit of phosphatidylinositol 3-kinase ErbB3 is overexpressed in a subset of human mammary tumors.
Host
Rabbit
Reactivity
Human, Mouse
Applications
ELISA, WB, IHC, FCM
Conjugation
Unconjugated
V-Erb B2 Erythroblastic Leukemia Viral Oncogene Homolog 3 (ErbB3) Antibody (PE), Abbexa, abx270956
V-Erb B2 Erythroblastic Leukemia Viral Oncogene Homolog 3 (ErbB3) Antibody (PE) is a Rabbit Polyclonal Antibody conjugated to PE against V-Erb B2 Erythroblastic Leukemia Viral Oncogene Homolog 3 (ErbB3) for use in flow cytometry.
Host
Rabbit
Reactivity
Mouse
Applications
FCM
Conjugation
PE
V-Erb B2 Erythroblastic Leukemia Viral Oncogene Homolog 3 (ErbB3) Antibody (APC), Abbexa, abx270724
V-Erb B2 Erythroblastic Leukemia Viral Oncogene Homolog 3 (ErbB3) Antibody (APC) is a Rabbit Polyclonal Antibody conjugated to APC against V-Erb B2 Erythroblastic Leukemia Viral Oncogene Homolog 3 (ErbB3) for use in flow cytometry.
Host
Rabbit
Reactivity
Mouse
Applications
FCM
Conjugation
APC
V-Erb B2 Erythroblastic Leukemia Viral Oncogene Homolog 3 (ErbB3) Antibody (Biotin), Abbexa, abx274304
V-Erb B2 Erythroblastic Leukemia Viral Oncogene Homolog 3 (ErbB3) Antibody (Biotin) is a Rabbit Polyclonal antibody conjugated to Biotin against V-Erb B2 Erythroblastic Leukemia Viral Oncogene Homolog 3 (ErbB3).
Host
Rabbit
Reactivity
Mouse
Applications
WB, IHC, IF/ICC
Conjugation
Biotin
V-Erb B2 Erythroblastic Leukemia Viral Oncogene Homolog 3 (ErbB3) Antibody (FITC), Abbexa, abx270492
V-Erb B2 Erythroblastic Leukemia Viral Oncogene Homolog 3 (ErbB3) Antibody (FITC) is a Rabbit Polyclonal Antibody conjugated to FITC against V-Erb B2 Erythroblastic Leukemia Viral Oncogene Homolog 3 (ErbB3) for use in flow cytometry.
Host
Rabbit
Reactivity
Mouse
Applications
FCM
Conjugation
FITC
Human V-Erb B2 Erythroblastic Leukemia Viral Oncogene Homolog 3 (ErbB3) ELISA Kit, Abbexa, abx151441
Human V-Erb B2 Erythroblastic Leukemia Viral Oncogene Homolog 3 (ErbB3) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human ErbB3 concentrations in serum, plasma, tissue homogenates and other biological fluids. This assay has high sensitivity and excellent specificity for detection of V-Erb B2 Erythroblastic Leukemia Viral Oncogene Homolog 3 (ErbB3)No significant cross-reactivity or interference between V-Erb B2 Erythroblastic Leukemia Viral Oncogene Homolog 3 (ErbB3) and analogues was observed.
Host
Reactivity
Human
Applications
ELISA
Conjugation
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