Search results for tyrosine kinase
Protein Tyrosine Kinase 2 Beta (PTK2) Antibody, Abbexa, abx328722
PTK2 Antibody is a Rabbit Polyclonal against PTK2.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
Neurotrophic Receptor Tyrosine Kinase 1 (NTRK1) Antibody, Abbexa, abx025227
This gene encodes a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in this gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, mental retardation and cancer. Alternate transcriptional splice variants of this gene have been found, but only three have been characterized to date.
Host
Mouse
Reactivity
Mouse
Applications
ELISA, WB
Conjugation
Unconjugated
Muscle Skeletal Receptor Tyrosine Kinase (MUSK) Antibody, Abbexa, abx002025
MUSK Antibody is a Rabbit Polyclonal antibody against MUSK. This gene encodes a muscle-specific tyrosine kinase receptor. The encoded protein may play a role in clustering of the acetylcholine receptor in the postsynaptic neuromuscular junction. Mutations in this gene have been associated with congenital myasthenic syndrome. Alternatively spliced transcript variants have been described.
Host
Rabbit
Reactivity
Mouse
Applications
WB
Conjugation
Unconjugated
Protein Tyrosine Kinase 2 Beta (PTK2) Antibody, Abbexa, abx328971
PTK2 Antibody is a Rabbit Polyclonal against PTK2.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
Protein Tyrosine Kinase 6 (PTK6) Antibody (FITC), Abbexa, abx316201
PTK6 Antibody (FITC) is a Rabbit Polyclonal against PTK6 conjugated to FITC.
Host
Rabbit
Reactivity
Human
Applications
Conjugation
FITC
Protein Tyrosine Kinase 2 Beta (PTK2) Antibody, Abbexa, abx122077
Rabbit Polyclonal against the PTK2 protein.
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB
Conjugation
Unconjugated
Protein Tyrosine Kinase 6 (PTK6) Antibody (Biotin), Abbexa, abx316202
PTK6 Antibody (Biotin) is a Rabbit Polyclonal against PTK6 conjugated to Biotin.
Host
Rabbit
Reactivity
Human
Applications
ELISA
Conjugation
Biotin
Protein-Tyrosine Kinase 2-Beta (Ptk2b) Antibody, Abbexa, abx027934
Involved in calcium induced regulation of ion channel and activation of the map kinase signaling pathway. May represent an important signaling intermediate between neuropeptide activated receptors or neurotransmitters that increase calcium flux and the downstream signals that regulate neuronal activity. Interacts with the SH2 domain of Grb2. May phosphorylate the voltage-gated potassium channel protein Kv1.2. Its activation is highly correlated with the stimulation of c-Jun N-terminal kinase activity. Involved in osmotic stress-dependent SNCA 'Tyr-125' phosphorylation (By similarity).
Host
Rabbit
Reactivity
Human, Mouse
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
Protein Tyrosine Kinase 2 Beta (PTK2) Antibody, Abbexa, abx011975
This gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal transduction pathways triggered in response to certain neural peptides or to cell interactions with the extracellular matrix. At least four transcript variants encoding four different isoforms have been found for this gene, but the full-length natures of only two of them have been determined. Tissue specificity: Expressed in all organs tested, in lymphoid cell lines, but most abundantly in brain.RD: Focal adhesion kinase 1 (FAK) is a ubiquitously expressed non-receptor protein tyrosine kinase that is concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. This cellular localization is directed by a Focal Adhesion Targeting (FAT) sequence, a 125 amino acid sequence at the C-terminus. FAK plays an important role in migration, cell spreading, differentiation, cytoskeleton protein phosphorylation, apoptosis and acceleration of the G1 to S phase transition of the cell cycle. It associates with several different signaling proteins such as Src-family PTKs, p130Cas, Shc, Grb2, PI 3-kinase, and paxillin. This enables FAK to function within a network of integrin-stimulated signaling pathways leading to the activation of targets such as the ERK and JNK/mitogen-activated protein kinase pathways. FAK is also linked to oncogenes at biochemical and functional levels. Increased expression and/or activity of FAK in various tumors has been correlated with enhanced migration and invasiveness of human tumor cells in addition to promoting increased cell proliferation.
Host
Mouse
Reactivity
Human
Applications
ELISA
Conjugation
Unconjugated
Protein Tyrosine Kinase 2 Beta (PTK2) Antibody, Abbexa, abx214724
PTK2 Antibody is a Rabbit Polyclonal against PTK2.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
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