Search results for Cellular tumor antigen p53
Cellular Tumor Antigen p53 Acetyl-Lys381 (TP53 AcK381) Antibody, Abbexa, abx326734
Acetyl-TP53 (K381) Antibody is a Rabbit Polyclonal against Acetyl-TP53 (K381).
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB, IHC, IF/ICC
Conjugation
Unconjugated
Cellular Tumor Antigen p53 Phospho-Ser366 (TP53 pS366) Antibody, Abbexa, abx324485
TP53 (pS366) Antibody is a Rabbit Polyclonal against TP53 (pS366).
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
Cellular Tumor Antigen p53 Phospho-Ser315 (TP53 pS315) Antibody, Abbexa, abx031896
Tumor protein p53, a nuclear protein, plays an essential role in the regulation of cell cycle, specifically in the transition from G0 to G1. It is found in very low levels in normal cells, however, in a variety of transformed cell lines, it is expressed in high amounts, and believed to contribute to transformation and malignancy. p53 is a DNA-binding protein containing DNA-binding, oligomerization and transcription activation domains. It is postulated to bind as a tetramer to a p53-binding site and activate expression of downstream genes that inhibit growth and/or invasion, and thus function as a tumor suppressor. Mutants of p53 that frequently occur in a number of different human cancers fail to bind the consensus DNA binding site, and hence cause the loss of tumor suppressor activity. Alterations of the TP53 gene occur not only as somatic mutations in human malignancies, but also as germline mutations in some cancer-prone families with Li-Fraumeni syndrome.
Host
Rabbit
Reactivity
Human
Applications
ELISA, IHC, DB
Conjugation
Unconjugated
Cellular Tumor Antigen p53 Phospho-Ser15 (TP53 pS15) Antibody, Abbexa, abx330206
TP53 (pS15) Antibody is a Rabbit Polyclonal against TP53 (pS15).
Host
Rabbit
Reactivity
Human, Rat
Applications
ELISA, WB, IHC, IF/ICC, IP
Conjugation
Unconjugated
Cellular Tumor Antigen p53 Phospho-Thr18 (TP53 pT18) Antibody, Abbexa, abx031899
Tumor protein p53, a nuclear protein, plays an essential role in the regulation of cell cycle, specifically in the transition from G0 to G1. It is found in very low levels in normal cells, however, in a variety of transformed cell lines, it is expressed in high amounts, and believed to contribute to transformation and malignancy. p53 is a DNA-binding protein containing DNA-binding, oligomerization and transcription activation domains. It is postulated to bind as a tetramer to a p53-binding site and activate expression of downstream genes that inhibit growth and/or invasion, and thus function as a tumor suppressor. Mutants of p53 that frequently occur in a number of different human cancers fail to bind the consensus DNA binding site, and hence cause the loss of tumor suppressor activity. Alterations of the TP53 gene occur not only as somatic mutations in human malignancies, but also as germline mutations in some cancer-prone families with Li-Fraumeni syndrome.
Host
Rabbit
Reactivity
Human, Mouse
Applications
ELISA, WB, IHC, DB
Conjugation
Unconjugated
Cellular Tumor Antigen p53 Phospho-Ser15 (TP53 pS15) Antibody, Abbexa, abx012560
Rabbit polyclonal antibody against p53 protein. Immunogen region is N-terminal. Specificity is as follows for the reactive species: H:S15, R:S15.
Host
Rabbit
Reactivity
Human, Rat
Applications
ELISA, WB, IHC, IP
Conjugation
Unconjugated
Cellular Tumor Antigen p53 Phospho-Ser315 (TP53 pS315) Antibody, Abbexa, abx332883
TP53 (pS315) Antibody is a Rabbit Polyclonal against TP53 (pS315).
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB, IHC, IF/ICC
Conjugation
Unconjugated
Cellular Tumor Antigen p53 Acetyl-Lys373 (TP53 AcK373) Antibody, Abbexa, abx323605
Acetyl-TP53 (K373) Antibody is a Rabbit Polyclonal against Acetyl-TP53 (K373).
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB
Conjugation
Unconjugated
Cellular Tumor Antigen p53 Phospho-Thr55 (TP53 pT55) Antibody, Abbexa, abx032008
Tumor protein p53, a nuclear protein, plays an essential role in the regulation of cell cycle, specifically in the transition from G0 to G1. It is found in very low levels in normal cells, however, in a variety of transformed cell lines, it is expressed in high amounts, and believed to contribute to transformation and malignancy. p53 is a DNA-binding protein containing DNA-binding, oligomerization and transcription activation domains. It is postulated to bind as a tetramer to a p53-binding site and activate expression of downstream genes that inhibit growth and/or invasion, and thus function as a tumor suppressor. Mutants of p53 that frequently occur in a number of different human cancers fail to bind the consensus DNA binding site, and hence cause the loss of tumor suppressor activity. Alterations of the TP53 gene occur not only as somatic mutations in human malignancies, but also as germline mutations in some cancer-prone families with Li-Fraumeni syndrome.
Host
Rabbit
Reactivity
Human
Applications
ELISA, DB
Conjugation
Unconjugated
Cellular Tumor Antigen p53 Phospho-Thr18 (TP53 pT18) Antibody, Abbexa, abx332933
TP53 (pT18) Antibody is a Rabbit Polyclonal against TP53 (pT18).
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB
Conjugation
Unconjugated
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