Search results for tyrosine kinase

PTK2 Protein Tyrosine Kinase 2 (FAK) Antibody, Abbexa, abx232950
FAK Antibody is a Rabbit Polyclonal against FAK.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB, IHC
Conjugation
Unconjugated

Protein Tyrosine Kinase 2 Beta (PTK2) Antibody, Abbexa, abx015854
This gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents.The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies.Activation of this gene may be an important early step in cell growth and intracellular signal transduction pathways triggered in response to certain neural peptides or to cell interactions with the extracellular matrix.At least four transcript variants encoding four different isoforms have been found for this gene, but the full-length natures of only two of them have been determined.Tissue specificity: Expressed in all organs tested, in lymphoid cell lines, but most abundantly in brain.RD: Focal adhesion kinase 1 (FAK) is a ubiquitously expressed non-receptor protein tyrosine kinase that is concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents.This cellular localization is directed by a Focal Adhesion Targeting (FAT) sequence, a 125 amino acid sequence at the C-terminus.FAK plays an important role in migration, cell spreading, differentiation, cytoskeleton protein phosphorylation, apoptosis and acceleration of the G1 to S phase transition of the cell cycle.It associates with several different signaling proteins such as Src-family PTKs, p130Cas, Shc, Grb2, PI 3-kinase, and paxillin.This enables FAK to function within a network of integrin-stimulated signaling pathways leading to the activation of targets such as the ERK and JNK/mitogen-activated protein kinase pathways.FAK is also linked to oncogenes at biochemical and functional levels.Increased expression and/or activity of FAK in various tumors has been correlated with enhanced migration and invasiveness of human tumor cells in addition to promoting increased cell proliferation.
Host
Mouse
Reactivity
Human
Applications
ELISA, IF/ICC, FCM
Conjugation
Unconjugated

Neurotrophic Tyrosine Kinase, Receptor, Type 2 Antibody, Abbexa, abx114090
Neurotrophic Tyrosine Kinase, Receptor, Type 2 Antibody is a Rabbit Polyclonal antibody against Neurotrophic Tyrosine Kinase, Receptor, Type 2.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB
Conjugation
Unconjugated

Tyrosine Kinase, Non Receptor 2 (TNK2) Antibody, Abbexa, abx178791
Tyrosine Kinase, Non Receptor 2 (TNK2) Antibody is a Rabbit Polyclonal antibody against Tyrosine Kinase, Non Receptor 2 (TNK2).
Host
Rabbit
Reactivity
Human
Applications
WB, IHC, IF/ICC
Conjugation
Unconjugated

ALK Tyrosine Kinase Receptor (ALK) Antibody (Biotin), Abbexa, abx316160
ALK Antibody (Biotin) is a Rabbit Polyclonal against ALK conjugated to Biotin.
Host
Rabbit
Reactivity
Human
Applications
ELISA
Conjugation
Biotin

ALK Tyrosine Kinase Receptor (ALK) Antibody (FITC), Abbexa, abx316159
ALK Antibody (FITC) is a Rabbit Polyclonal against ALK conjugated to FITC.
Host
Rabbit
Reactivity
Human
Applications
Conjugation
FITC

Muscle, Skeletal, Receptor Tyrosine Kinase (MUSK) Antibody, Abbexa, abx177636
This product is currently in development. The lead time for this product may be several months. Please contact us at [email protected] for an updated lead time before purchasing this product. Muscle, Skeletal, Receptor Tyrosine Kinase (MUSK) Antibody is a Rabbit Polyclonal antibody against Muscle, Skeletal, Receptor Tyrosine Kinase (MUSK).
Host
Rabbit
Reactivity
Human
Applications
WB, IHC, IF/ICC
Conjugation
Unconjugated

Human Bruton'S Tyrosine Kinase (Btk) ELISA Kit, Abbexa, abx150845
Human Bruton'S Tyrosine Kinase (Btk) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Bruton'S Tyrosine Kinase (Btk) concentrations in tissue homogenates, cell lysates and other biological fluids. This assay has high sensitivity and excellent specificity for detection of Bruton'S Tyrosine Kinase (Btk)No significant cross-reactivity or interference between Bruton'S Tyrosine Kinase (Btk) and analogues was observed.
Host
Reactivity
Human
Applications
ELISA
Conjugation

Human Tyrosine Kinase 2 (TYK2) ELISA Kit, Abbexa, abx253334
Human Tyrosine Kinase 2 (TYK2) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Tyrosine Kinase 2 concentrations in serum, plasma and other biological fluids.
Host
Reactivity
Human
Applications
ELISA
Conjugation

Tyrosine Kinase Non Receptor 1 (TNK1) Antibody, Abbexa, abx025220
Involved in negative regulation of cell growth. Has tumor suppressor properties. Plays a negative regulatory role in the Ras-MAPK pathway. May function in signaling pathways utilized broadly during fetal development and more selectively in adult tissues and in cells of the lymphohematopoietic system. Could specifically be involved in phospholipid signal transduction.
Host
Mouse
Reactivity
Mouse
Applications
ELISA, WB
Conjugation
Unconjugated
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