Search results for ATG4A antibody
Cysteine Protease ATG4A (ATG4A) Antibody, Abbexa, abx148394
Cysteine Protease ATG4A (ATG4A) Antibody is a Rabbit Polyclonal antibody for the detection of ATG4A.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB
Conjugation
Unconjugated
Cysteine Protease ATG4A (ATG4A) Antibody, Abbexa, abx030004
Macroautophagy is the major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane bound autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane bound structure, which then fuse with the lysosome (or vacuole) releasing a single-membrane bound autophagic bodies which are then degraded within the lysosome (or vacuole). APG4A is a cysteine protease required for autophagy, which cleaves the C-terminal part of either MAP1LC3, GABARAPL2 or GABARAP, allowing the liberation of form I. A subpopulation of form I is subsequently converted to a smaller form (form II). Form II, with a revealed C-terminal glycine, is considered to be the phosphatidylethanolamine (PE) conjugated form, and has the capacity for the binding to autophagosomes. Preferred substrate is GABARAPL2 followed by MAP1LC3A and GABARAP.
Host
Rabbit
Reactivity
Human, Mouse
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
Cysteine Protease ATG4A (ATG4A) Antibody, Abbexa, abx432377
ATG4A Antibody is a Goat Polyclonal antibody against ATG4A.
Host
Goat
Reactivity
Human
Applications
P-ELISA, IHC
Conjugation
Unconjugated
Cysteine Protease ATG4A (ATG4A) Antibody, Abbexa, abx317909
ATG4A Antibody is a Rabbit Polyclonal against ATG4A.
Host
Rabbit
Reactivity
Human, Mouse
Applications
ELISA, WB
Conjugation
Unconjugated
Cysteine Protease ATG4A (ATG4A) Antibody, Abbexa, abx002031
ATG4A Antibody is a Rabbit Polyclonal antibody against ATG4A. Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54 family of cysteine proteases. Transcript variants that encode distinct isoforms have been identified.
Host
Rabbit
Reactivity
Human, Mouse
Applications
WB
Conjugation
Unconjugated
Cysteine Protease ATG4A (ATG4A) Antibody, Abbexa, abx122574
Rabbit Polyclonal against the ATG4A protein.
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
Cysteine Protease ATG4A (ATG4A) Antibody, Abbexa, abx030003
Macroautophagy is the major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane bound autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane bound structure, which then fuse with the lysosome (or vacuole) releasing a single-membrane bound autophagic bodies which are then degraded within the lysosome (or vacuole). APG4A is a cysteine protease required for autophagy, which cleaves the C-terminal part of either MAP1LC3, GABARAPL2 or GABARAP, allowing the liberation of form I. A subpopulation of form I is subsequently converted to a smaller form (form II). Form II, with a revealed C-terminal glycine, is considered to be the phosphatidylethanolamine (PE) conjugated form, and has the capacity for the binding to autophagosomes. Preferred substrate is GABARAPL2 followed by MAP1LC3A and GABARAP.
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
Cysteine Protease ATG4A (ATG4A) Antibody, Abbexa, abx030002
Macroautophagy is the major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane bound autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane bound structure, which then fuse with the lysosome (or vacuole) releasing a single-membrane bound autophagic bodies which are then degraded within the lysosome (or vacuole). APG4A is a cysteine protease required for autophagy, which cleaves the C-terminal part of either MAP1LC3, GABARAPL2 or GABARAP, allowing the liberation of form I. A subpopulation of form I is subsequently converted to a smaller form (form II). Form II, with a revealed C-terminal glycine, is considered to be the phosphatidylethanolamine (PE) conjugated form, and has the capacity for the binding to autophagosomes. Preferred substrate is GABARAPL2 followed by MAP1LC3A and GABARAP.
Host
Rabbit
Reactivity
Human, Mouse
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
Cysteine Protease ATG4A (ATG4A) Antibody, Abbexa, abx014407
Rabbit polyclonal antibody against ATG4A protein. Immunogen region is Internal.
Host
Rabbit
Reactivity
Human, Mouse
Applications
ELISA, IHC, IF/ICC
Conjugation
Unconjugated
ATG4A Antibody (YA601)(PBS only), MedChemexpress, HY-P80557A
ATG4A Antibody (YA601) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to ATG4A.
Host
Rabbit
Reactivity
Human
Applications
WB, IHC-P, IP
Conjugation
Non-conjugated
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