Search results for Advanced Glycosylation End Product-Specific Receptor (AGER) Antibody
Advanced Glycosylation End Product-Specific Receptor (AGER) Antibody, Abbexa, abx324550
AGER Antibody is a Rabbit Polyclonal against AGER.
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
Advanced Glycosylation End Product-Specific Receptor (AGER) Antibody, Abbexa, abx239942
Advanced Glycosylation End Product-Specific Receptor (AGER) Antibody is a Mouse Monoclonal antibody for the detection of AGER. Mediates interactions of advanced glycosylation end products (AGE). These are nonenzymatically glycosylated proteins which accumulate in vascular tissue in aging and at an accelerated rate in diabetes. Acts as a mediator of both acute and chronic vascular inflammation in conditions such as atherosclerosis and in particular as a complication of diabetes. AGE/RAGE signaling plays an important role in regulating the production/expression of TNF-alpha, oxidative stress, and endothelial dysfunction in type 2 diabetes. Interaction with S100A12 on endothelium, mononuclear phagocytes, and lymphocytes triggers cellular activation, with generation of key proinflammatory mediators. Interaction with S100B after myocardial infarction may play a role in myocyte apoptosis by activating ERK1/2 and p53/TP53 signaling (By similarity). Receptor for amyloid beta peptide. Contributes to the translocation of amyloid-beta peptide (ABPP) across the cell membrane from the extracellular to the intracellular space in cortical neurons. ABPP-initiated RAGE signaling, especially stimulation of p38 mitogen-activated protein kinase (MAPK), has the capacity to drive a transport system delivering ABPP as a complex with RAGE to the intraneuronal space. Can also bind oligonucleotides.
Host
Mouse
Reactivity
Human, Rat
Applications
ELISA, WB
Conjugation
Unconjugated
Advanced Glycosylation End Product Specific Receptor (AGER) Antibody, Abbexa, abx036573
Rabbit Polyclonal against the AGER protein.
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
Advanced Glycosylation End Product-Specific Receptor (AGER) Antibody, Abbexa, abx001218
AGER Antibody is a Rabbit Polyclonal antibody against AGER. The advanced glycosylation end product (AGE) receptor encoded by this gene is a member of the immunoglobulin superfamily of cell surface receptors. It is a multiligand receptor, and besides AGE, interacts with other molecules implicated in homeostasis, development, and inflammation, and certain diseases, such as diabetes and Alzheimer's disease. Many alternatively spliced transcript variants encoding different isoforms, as well as non-protein-coding variants, have been described for this gene (PMID:18089847).
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
WB
Conjugation
Unconjugated
Advanced Glycosylation End Product Specific Receptor (AGER) Antibody, Abbexa, abx171123
This product is currently in development. The lead time for this product may be several months. Please contact us at [email protected] for an updated lead time before purchasing this product. Advanced Glycosylation End Product Specific Receptor (AGER) Antibody is a Mouse Monoclonal antibody against Advanced Glycosylation End Product Specific Receptor (AGER).
Host
Mouse
Reactivity
Human
Applications
WB, IHC, IF/ICC
Conjugation
Unconjugated
Advanced Glycosylation End Product-Specific Receptor (AGER) Antibody, Abbexa, abx211205
AGER Antibody is a Rabbit Polyclonal against AGER.
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
Advanced Glycosylation End Product-Specific Receptor (AGER) Antibody, Abbexa, abx456353
Advanced Glycosylation End Product-Specific Receptor (AGER) Antibody is a Rabbit polyclonal antibody for the detection of Mouse Advanced Glycosylation End Product-Specific Receptor (AGER).
Host
Rabbit
Reactivity
Mouse
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
Advanced Glycosylation End Product-Specific Receptor (AGER) Antibody, Abbexa, abx020069
Advanced Glycosylation End Product-Specific Receptor (AGER) Antibody is a Rabbit Polyclonal antibody for the detection of AGER. Mediates interactions of advanced glycosylation end products (AGE). These are nonenzymatically glycosylated proteins which accumulate in vascular tissue in aging and at an accelerated rate in diabetes. Acts as a mediator of both acute and chronic vascular inflammation in conditions such as atherosclerosis and in particular as a complication of diabetes. AGE/RAGE signaling plays an important role in regulating the production/expression of TNF-alpha, oxidative stress, and endothelial dysfunction in type 2 diabetes. Interaction with S100A12 on endothelium, mononuclear phagocytes, and lymphocytes triggers cellular activation, with generation of key proinflammatory mediators. Interaction with S100B after myocardial infarction may play a role in myocyte apoptosis by activating ERK1/2 and p53/TP53 signaling (By similarity). Receptor for amyloid beta peptide. Contributes to the translocation of amyloid-beta peptide (ABPP) across the cell membrane from the extracellular to the intracellular space in cortical neurons. ABPP-initiated RAGE signaling, especially stimulation of p38 mitogen-activated protein kinase (MAPK), has the capacity to drive a transport system delivering ABPP as a complex with RAGE to the intraneuronal space. Can also bind oligonucleotides.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
Advanced Glycosylation End Product Specific Receptor (AGER) Antibody, Abbexa, abx230209
Advanced Glycosylation End Product Specific Receptor (AGER) Antibody is a Rabbit polyclonal against Advanced Glycosylation End Product Specific Receptor (AGER). AGER mediates interactions of advanced glycosylation end products (AGE), non-enzymatically glycosylated proteins that accumulate in vascular tissue in aging and at an accelerated rate in diabetes. AGER is a mediator of both acute and chronic vascular inflammation in conditions such as atherosclerosis and in particular as a complication of diabetes. AGE/RAGE signaling plays an important role in regulating the production/expression of TNF-alpha, oxidative stress, and endothelial dysfunction in type 2 diabetes. It interacts with S100A12 on endothelium, mononuclear phagocytes and lymphocytes, triggers cellular activation and generates important proinflammatory mediators. It is a receptor for amyloid beta peptide and facilitates its translocation across the cell membrane from the extracellular to the intracellular space in cortical neurons. ABPP-initiated RAGE signaling, especially stimulation of p38 mitogen-activated protein kinase(MAPK), has the capacity to drive a transport system delivering ABPP asa complex with RAGE to the intraneuronal space. AGER also binds oligonucleotides.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
Advanced Glycosylation End Product-Specific Receptor (AGER) Antibody (Biotin), Abbexa, abx105108
Advanced glycosylation end product-specific receptor Antibody (Biotin) is a Rabbit Polyclonal antibody against Advanced glycosylation end product-specific receptor conjugated to Biotin.
Host
Rabbit
Reactivity
Human
Applications
ELISA
Conjugation
Biotin
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