Search results for BRCA2 antibody
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Anti-BRCA2 antibody [EPR29007-533], Abcam, AB324270
Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents . What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies .
Host
Rabbit
Reactivity
Mouse
Applications
WB
Conjugation
Breast Cancer Susceptibility Protein 2 (BRCA2) Antibody, Abbexa, abx171477
This product is currently in development. The lead time for this product may be several months. Please contact us at [email protected] for an updated lead time before purchasing this product. Breast Cancer Susceptibility Protein 2 (BRCA2) Antibody is a Mouse Monoclonal antibody against Breast Cancer Susceptibility Protein 2 (BRCA2).
Host
Mouse
Reactivity
Human
Applications
WB, IHC, IF/ICC
Conjugation
Unconjugated
Breast Cancer Susceptibility Protein 2 (BRCA2) Antibody, Abbexa, abx129746
Breast Cancer Susceptibility Protein 2 Antibody is a Rabbit Polyclonal against Breast Cancer Susceptibility Protein 2.
Host
Rabbit
Reactivity
Mouse
Applications
WB, IHC, IF/ICC
Conjugation
Unconjugated
Breast Cancer Susceptibility Protein 2 (BRCA2) Antibody, Abbexa, abx130340
Breast Cancer Susceptibility Protein 2 Antibody is a Rabbit Polyclonal against Breast Cancer Susceptibility Protein 2.
Host
Rabbit
Reactivity
Rat
Applications
WB, IHC, IF/ICC
Conjugation
Unconjugated
Breast Cancer Type 2 Susceptibility Protein (BRCA2) Antibody, Abbexa, abx240132
Breast Cancer Type 2 Susceptibility Protein (BRCA2) Antibody is a Rabbit Polyclonal antibody for the detection of BRCA2. Involved in double-strand break repair and/or homologous recombination. Binds RAD51 and potentiates recombinational DNA repair by promoting assembly of RAD51 onto single-stranded DNA (ssDNA). Acts by targeting RAD51 to ssDNA over double-stranded DNA, enabling RAD51 to displace replication protein-A (RPA) from ssDNA and stabilizing RAD51-ssDNA filaments by blocking ATP hydrolysis. Part of a PALB2-scaffolded HR complex containing RAD51C and which is thought to play a role in DNA repair by HR. May participate in S phase checkpoint activation. Binds selectively to ssDNA, and to ssDNA in tailed duplexes and replication fork structures. May play a role in the extension step after strand invasion at replication-dependent DNA double-strand breaks; together with PALB2 is involved in both POLH localization at collapsed replication forks and DNA polymerization activity. In concert with NPM1, regulates centrosome duplication. Interacts with the TREX-2 complex (transcription and export complex 2) subunits PCID2 and SHFM1/DSS1, and is required to prevent R-loop-associated DNA damage and thus transcription-associated genomic instability. Silencing of BRCA2 promotes R-loop accumulation at actively transcribed genes in replicating and non-replicating cells, suggesting that BRCA2 mediates the control of R-loop associated genomic instability, independently of its known role in homologous recombination (PubMed:24896180).
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB
Conjugation
Unconjugated
Breast Cancer Type 2 Susceptibility Protein (BRCA2) Antibody, Abbexa, abx013516
Rabbit polyclonal antibody against BRCA2 protein. Immunogen region is N-terminal.
Host
Rabbit
Reactivity
Human, Rat
Applications
ELISA, IHC
Conjugation
Unconjugated
Breast Cancer Type 2 Susceptibility Protein (BRCA2) Antibody, Abbexa, abx210630
BRCA2 Antibody is a Rabbit Polyclonal against BRCA2.
Host
Rabbit
Reactivity
Human
Applications
ELISA, IHC
Conjugation
Unconjugated
Breast Cancer Type 2 Susceptibility Protein (BRCA2) Antibody, Abbexa, abx455498
Breast Cancer Type 2 Susceptibility Protein (BRCA2) Antibody is a Rabbit polyclonal antibody for the detection of Human Breast Cancer Type 2 Susceptibility Protein (BRCA2).
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
Breast Cancer Type 2 Susceptibility Protein (BRCA2) Antibody, Abbexa, abx123420
BRCA2 Antibody is a Rabbit Polyclonal Antibody against BRCA2.
Host
Rabbit
Reactivity
Human, Rat
Applications
IF/ICC
Conjugation
Unconjugated
Anti-BRCA2 antibody [EPR23442-43] - BSA and Azide free, Abcam, AB273157
ab273157 is the carrier-free version of ab239375 . Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents . What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies . Conjugation ready Our carrier-free antibodies are typically supplied in a PBS-only formulation, purified and free of BSA, sodium azide and glycerol. This conjugation-ready format is designed for use with fluorochromes, metal isotopes, oligonucleotides, and enzymes, which makes them ideal for antibody labelling, functional and cell-based assays, flow-based assays (e.g. mass cytometry) and Multiplex Imaging applications. Use our conjugation kits for antibody conjugates that are ready-to-use in as little as 20 minutes with 1 minute hands-on-time and 100% antibody recovery: available for fluorescent dyes, HRP, biotin and gold. Compatibility This product is compatible with the Maxpar ® Antibody Labeling Kit from Fluidigm, without the need for antibody preparation. Maxpar ® is a trademark of Fluidigm Canada Inc.
Host
Rabbit
Reactivity
Human
Applications
WB
Conjugation
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