Search results for Bone Morphogenetic Protein Receptor 1A (BMPR1A) Antibody
Bone Morphogenetic Protein Receptor 1A (BMPR1A) Antibody, Abbexa, abx031354
The bone morphogenetic protein (BMP) receptors belong to a family of transmembrane serine/threonine kinases including the type I receptors BMPR1A and BMPR1B and the type II receptor BMPR2. These receptors are also closely related to the activin receptors, ACVR1 and ACVR2. The ligands of these receptors are members of the TGF-beta superfamily. Both activins and TGF-beta transduce their signals through the formation of heteromeric complexes with 2 different types of serine (threonine) kinase receptors. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. BMP receptors are highly expressed in bone, skeletal muscle, heart and liver tissue. BMPRs play a crucial role during development as mutations or deletions to the BMPR genes can cause juvenile polyposis, disrupt normal dorsal/ventral patterning during limb development, and may be a factor in the progession of Cowden-like syndrome. Germline mutations in the BMPR2 gene encoding bone morphogenetic protein (BMP) type II receptor (BMPR-II) have been reported in patients with primary pulmonary hypertension (PPH).
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB, IF/ICC
Conjugation
Unconjugated
Bone Morphogenetic Protein Receptor 1A (BMPR1A) Antibody, Abbexa, abx036683
Rabbit Polyclonal against the BMPR1A protein.
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
Bone Morphogenetic Protein Receptor 1A (BMPR1A) Antibody, Abbexa, abx031355
The bone morphogenetic protein (BMP) receptors are a family of transmembrane serine/threonine kinases that include the type I receptors BMPR1A and BMPR1B and the type II receptor BMPR2. These receptors are also closely related to the activin receptors, ACVR1 and ACVR2. The ligands of these receptors are members of the TGF-beta superfamily. TGF-betas and activins transduce their signals through the formation of heteromeric complexes with 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding.
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
Bone Morphogenetic Protein Receptor 1A (BMPR1A) Antibody, Abbexa, abx171452
This product is currently in development. The lead time for this product may be several months. Please contact us at [email protected] for an updated lead time before purchasing this product. Bone Morphogenetic Protein Receptor 1A (BMPR1A) Antibody is a Mouse Monoclonal antibody against Bone Morphogenetic Protein Receptor 1A (BMPR1A).
Host
Mouse
Reactivity
Rat
Applications
WB, IHC, IF/ICC
Conjugation
Unconjugated
Bone Morphogenetic Protein Receptor 1A (BMPR1A) Antibody, Abbexa, abx130231
Bone Morphogenetic Protein Receptor 1A Antibody is a Rabbit Polyclonal against Bone Morphogenetic Protein Receptor 1A.
Host
Rabbit
Reactivity
Rat
Applications
WB, IHC, IF/ICC
Conjugation
Unconjugated
Bone Morphogenetic Protein Receptor 1A (BMPR1A) Antibody, Abbexa, abx031356
The bone morphogenetic protein (BMP) receptors are a family of transmembrane serine/threonine kinases that include the type I receptors BMPR1A and BMPR1B and the type II receptor BMPR2. These receptors are also closely related to the activin receptors, ACVR1 and ACVR2. The ligands of these receptors are members of the TGF-beta superfamily. TGF-betas and activins transduce their signals through the formation of heteromeric complexes with 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. BMPRIA binds BMP4 with high-affinity in solution and is a potent BMP-4 antagonist in vitro. In adult tissues, BMPRIA is widely expressed, with the highest expression levels detected in skeletal muscle. BMPRIA is also widely expressed during embryogenesis.
Host
Rabbit
Reactivity
Human, Mouse
Applications
ELISA, WB, FCM
Conjugation
Unconjugated
Bone Morphogenetic Protein Receptor 1A (BMPR1A) Antibody (Biotin), Abbexa, abx303213
BMPR1A Antibody (Biotin) is a Rabbit Polyclonal against BMPR1A conjugated to Biotin.
Host
Rabbit
Reactivity
Human
Applications
ELISA
Conjugation
Biotin
Bone Morphogenetic Protein Receptor 1A (BMPR1A) Antibody (HRP), Abbexa, abx303211
BMPR1A Antibody (HRP) is a Rabbit Polyclonal against BMPR1A conjugated to HRP.
Host
Rabbit
Reactivity
Human
Applications
ELISA
Conjugation
HRP
Bone Morphogenetic Protein Receptor 1A (BMPR1A) Antibody (FITC), Abbexa, abx303212
BMPR1A Antibody (FITC) is a Rabbit Polyclonal against BMPR1A conjugated to FITC.
Host
Rabbit
Reactivity
Human
Applications
Conjugation
FITC
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