Search results for CHFR antibody
E3 Ubiquitin-Protein Ligase CHFR (CHFR) Antibody, Abbexa, abx028051
E3 ubiquitin-protein ligase that functions in the antephase checkpoint by actively delaying passage into mitosis in response to microtubule poisons. Acts in early prophase before chromosome condensation, when the centrosome move apart from each other along the periphery of the nucleus. Probably involved in signaling the presence of mitotic stress caused by microtubule poisons by mediating the 'Lys-48'-linked ubiquitination of target proteins, leading to their degradation by the proteasome. Promotes the ubiquitination and subsequent degradation of AURKA and PLK1. Probably acts as a tumor suppressor, possibly by mediating the polyubiquitination of HDAC1, leading to its degradation. May also promote the formation of 'Lys-63'-linked polyubiquitin chains and functions with the specific ubiquitin-conjugating UBC13-MMS2 (UBE2N-UBE2V2) heterodimer. Substrates that are polyubiquitinated at 'Lys-63' are usually not targeted for degradation, but are rather involved in signaling cellular stress.
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB
Conjugation
Unconjugated
E3 Ubiquitin-Protein Ligase CHFR (CHFR) Antibody, Abbexa, abx125667
CHFR Antibody is a Rabbit Polyclonal against CHFR.
Host
Rabbit
Reactivity
Human, Mouse
Applications
WB
Conjugation
Unconjugated
E3 Ubiquitin-Protein Ligase CHFR (CHFR) Antibody, Abbexa, abx015114
Rabbit polyclonal antibody against CHFR protein. Immunogen region is Internal.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
WB
Conjugation
Unconjugated
E3 Ubiquitin-Protein Ligase CHFR (CHFR) Antibody (Biotin), Abbexa, abx314595
CHFR Antibody (Biotin) is a Rabbit Polyclonal against CHFR conjugated to Biotin.
Host
Rabbit
Reactivity
Human
Applications
ELISA
Conjugation
Biotin
E3 Ubiquitin-Protein Ligase CHFR (CHFR) Antibody (HRP), Abbexa, abx314593
CHFR Antibody (HRP) is a Rabbit Polyclonal against CHFR conjugated to HRP.
Host
Rabbit
Reactivity
Human
Applications
ELISA
Conjugation
HRP
E3 Ubiquitin-Protein Ligase CHFR (CHFR) Antibody (FITC), Abbexa, abx314594
CHFR Antibody (FITC) is a Rabbit Polyclonal against CHFR conjugated to FITC.
Host
Rabbit
Reactivity
Human
Applications
Conjugation
FITC
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