Search results for Cellular tumor antigen p53
Cellular Tumor Antigen p53 (TP53) Antibody, Abbexa, abx330036
TP53 Antibody is a Rabbit Polyclonal against TP53.
Host
Rabbit
Reactivity
Human, Mouse, Rat, Monkey
Applications
ELISA, WB, IHC, IF/ICC
Conjugation
Unconjugated
Cellular Tumor Antigen p53 (TP53) Antibody, Abbexa, abx327408
TP53 Antibody is a Rabbit Polyclonal against TP53.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB
Conjugation
Unconjugated
Cellular Tumor Antigen p53 (TP53) Antibody, Abbexa, abx032761
Tumor protein p53, a nuclear protein, plays an essential role in the regulation of cell cycle, specifically in the transition from G0 to G1. It is found in very low levels in normal cells, however, in a variety of transformed cell lines, it is expressed in high amounts, and believed to contribute to transformation and malignancy. p53 is a DNA-binding protein containing DNA-binding, oligomerization and transcription activation domains. It is postulated to bind as a tetramer to a p53-binding site and activate expression of downstream genes that inhibit growth and/or invasion, and thus function as a tumor suppressor. Mutants of p53 that frequently occur in a number of different human cancers fail to bind the consensus DNA binding site, and hence cause the loss of tumor suppressor activity. Alterations of the TP53 gene occur not only as somatic mutations in human malignancies, but also as germline mutations in some cancer-prone families with Li-Fraumeni syndrome.
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB, IHC, IF/ICC
Conjugation
Unconjugated
Cellular Tumor Antigen p53 (TP53) Antibody, Abbexa, abx402146
Cellular Tumor Antigen p53 (TP53) Antibody is a Recombinant Rabbit Monoclonal antibody for the detection of Human TP53.
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB, IHC, IF/ICC
Conjugation
Unconjugated
Cellular Tumor Antigen p53 (TP53) Antibody, Abbexa, abx403200
Human Cellular Tumor Antigen p53 (TP53) Antibody is a Mouse monoclonal against Cellular Tumor Antigen p53 (TP53).
Host
Mouse
Reactivity
Human
Applications
WB, IHC, IF/ICC
Conjugation
Unconjugated
Cellular Tumor Antigen p53 (TP53) Antibody, Abbexa, abx323268
TP53 Antibody is a Rabbit Polyclonal against TP53.
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB
Conjugation
Unconjugated
Cellular Tumor Antigen p53 (TP53) Antibody, Abbexa, abx011309
p53 responds to diverse cellular stresses to regulate target genes that induce cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. p53 protein is expressed at low level in normal cells and at a high level in a variety of transformed cell lines, where it's believed to contribute to transformation and malignancy. p53 is a DNA-binding protein containing transcription activation, DNA-binding, and oligomerization domains. It is postulated to bind to a p53-binding site and activate expression of downstream genes that inhibit growth and/or invasion, and thus function as a tumor suppressor. Mutants of p53 that frequently occur in a number of different human cancers fail to bind the consensus DNA binding site, and hence cause the loss of tumor suppressor activity. Alterations of this gene occur not only as somatic mutations in human malignancies, but also as germline mutations in some cancer-prone families with Li-Fraumeni syndrome. Multiple p53 variants due to alternative promoters and multiple alternative splicing have been found. These variants encode distinct isoforms, which can regulate p53 transcriptional activity.
Host
Mouse
Reactivity
Human
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
Cellular Tumor Antigen p53 (TP53) Antibody, Abbexa, abx145422
TP53 Antibody is a Rabbit Polyclonal against TP53.
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB
Conjugation
Unconjugated
Cellular Tumor Antigen p53 (TP53) Antibody, Abbexa, abx402336
Cellular Tumor Antigen p53 (TP53) Antibody is a Recombinant Rabbit Monoclonal antibody for the detection of Human TP53.
Host
Rabbit
Reactivity
Human
Applications
ELISA, IF/ICC
Conjugation
Unconjugated
Cellular Tumor Antigen p53 (TP53) Antibody, Abbexa, abx137175
Cellular Tumor Antigen p53 (p53) Antibody is a Mouse Monoclonal antibody against Cellular Tumor Antigen p53 (p53).
Host
Mouse
Reactivity
Human
Applications
Conjugation
Unconjugated
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