Search results for Chemokine C-X-C-Motif Receptor 3 (CXCR3) Antibody
Chemokine C-X-C-Motif Receptor 3 (CXCR3) Antibody, Abbexa, abx213831
CXCR3 Antibody is a Rabbit Polyclonal against CXCR3.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, IHC
Conjugation
Unconjugated
Chemokine C-X-C-Motif Receptor 3 (CXCR3) Antibody, Abbexa, abx119624
CXCR3 Antibody is a Rabbit Polyclonal antibody against CXCR3.
Host
Rabbit
Reactivity
Human
Applications
WB
Conjugation
Unconjugated
Chemokine C-X-C-Motif Receptor 3 (CXCR3) Antibody, Abbexa, abx025617
This gene encodes a G protein-coupled receptor with selectivity for three chemokines, termed IP10 (interferon-g-inducible 10 kDa protein), Mig (monokine induced by interferon-g) and I-TAC (interferon-inducible T cell a-chemoattractant). IP10, Mig and I-TAC belong to the structural subfamily of CXC chemokines, in which a single amino acid residue separates the first two of four highly conserved Cys residues. Binding of chemokines to this protein induces cellular responses that are involved in leukocyte traffic, most notably integrin activation, cytoskeletal changes and chemotactic migration. Inhibition by Bordetella pertussis toxin suggests that heterotrimeric G protein of the Gi-subclass couple to this protein. Signal transduction has not been further analyzed but may include the same enzymes that were identified in the signaling cascade induced by other chemokine receptors. As a consequence of chemokine-induced cellular desensitization (phosphorylation-dependent receptor internalization), cellular responses are typically rapid and short in duration. Cellular responsiveness is restored after dephosphorylation of intracellular receptors and subsequent recycling to the cell surface. This gene is prominently expressed in in vitro cultured effector/memory T cells, and in T cells present in many types of inflamed tissues. In addition, IP10, Mig and I-TAC are commonly produced by local cells in inflammatory lesion, suggesting that this gene and its chemokines participate in the recruitment of inflammatory cells. Therefore, this protein is a target for the development of small molecular weight antagonists, which may be used in the treatment of diverse inflammatory diseases. Multiple transcript variants encoding different isoforms have been found for this gene.
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB, IHC, FCM
Conjugation
Unconjugated
Chemokine C-X-C-Motif Receptor 3 (CXCR3) Antibody, Abbexa, abx147377
Chemokine C-X-C-Motif Receptor 3 (CXCR3) Antibody is a Rabbit Polyclonal antibody for the detection of CXCR3. This gene encodes a G protein-coupled receptor with selectivity for three chemokines, termed CXCL9/Mig (monokine induced by interferon-g), CXCL10/IP10 (interferon-g-inducible 10 kDa protein) and CXCL11/I-TAC (interferon-inducible T cell a-chemoattractant). Binding of chemokines to this protein induces cellular responses that are involved in leukocyte traffic, most notably integrin activation, cytoskeletal changes and chemotactic migration. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. One of the isoforms (CXCR3-B) shows high affinity binding to chemokine, CXCL4/PF4 (PMID:12782716).
Host
Rabbit
Reactivity
Human, Mouse
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
Chemokine C-X-C-Motif Receptor 3 (CXCR3) Antibody, Abbexa, abx175816
Chemokine C-X-C-Motif Receptor 3 (CXCR3) Antibody is a Rabbit Polyclonal antibody against Chemokine C-X-C-Motif Receptor 3 (CXCR3).
Host
Rabbit
Reactivity
Human
Applications
WB, IHC, IF/ICC
Conjugation
Unconjugated
Chemokine C-X-C-Motif Receptor 3 (CXCR3) Antibody (Biotin), Abbexa, abx312669
CXCR3 Antibody (Biotin) is a Rabbit Polyclonal against CXCR3 conjugated to Biotin.
Host
Rabbit
Reactivity
Human
Applications
ELISA
Conjugation
Biotin
Chemokine C-X-C-Motif Receptor 3 (CXCR3) Antibody (HRP), Abbexa, abx312667
CXCR3 Antibody (HRP) is a Rabbit Polyclonal against CXCR3 conjugated to HRP.
Host
Rabbit
Reactivity
Human
Applications
ELISA
Conjugation
HRP
Chemokine C-X-C-Motif Receptor 3 (CXCR3) Antibody (FITC), Abbexa, abx312668
CXCR3 Antibody (FITC) is a Rabbit Polyclonal against CXCR3 conjugated to FITC.
Host
Rabbit
Reactivity
Human
Applications
Conjugation
FITC
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