Search results for Crystallin Alpha B (CRYAB) Antibody
Crystallin Alpha B (CRYAB) Antibody, Abbexa, abx027544
Crystallins are separated into two classes: taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. Since lens central fiber cells lose their nuclei during development, these crystallins are made and then retained throughout life, making them extremely stable proteins. Mammalian lens crystallins are divided into alpha, beta, and gamma families; beta and gamma crystallins are also considered as a superfamily. Alpha and beta families are further divided into acidic and basic groups. Seven protein regions exist in crystallins: four homologous motifs, a connecting peptide, and N and C-terminal extensions. Alpha crystallins are composed of two gene products: alpha-A and alpha-B, for acidic and basic, respectively. Alpha crystallins can be induced by heat shock and are members of the small heat shock protein (sHSP also known as the HSP20) family. They act as molecular chaperones although they do not renature proteins and release them in the fashion of a true chaperone; instead they hold them in large soluble aggregates. Post-translational modifications decrease the ability to chaperone. These heterogeneous aggregates consist of 30-40 subunits; the alpha-A and alpha-B subunits have a 3:1 ratio, respectively. Two additional functions of alpha crystallins are an autokinase activity and participation in the intracellular architecture. Alpha-A and alpha-B gene products are differentially expressed; alpha-A is preferentially restricted to the lens and alpha-B is expressed widely in many tissues and organs. Elevated expression of alpha-B crystallin occurs in many neurological diseases; a missense mutation cosegregated in a family with a desmin-related myopathy.
Host
Rabbit
Reactivity
Human, Mouse
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
Crystallin Alpha B (CRYaB) Antibody, Abbexa, abx171953
This product is currently in development. The lead time for this product may be several months. Please contact us at [email protected] for an updated lead time before purchasing this product. Crystallin Alpha B (CRYaB) Antibody is a Mouse Monoclonal antibody against Crystallin Alpha B (CRYaB).
Host
Mouse
Reactivity
Human
Applications
WB, IHC, IF/ICC
Conjugation
Unconjugated
Crystallin Alpha B (CRYAB) Antibody, Abbexa, abx326620
CRYAB Antibody is a Rabbit Polyclonal against CRYAB.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, IHC
Conjugation
Unconjugated
Crystallin Alpha B (CRYaB) Antibody, Abbexa, abx176046
Crystallin Alpha B (CRYaB) Antibody is a Rabbit Polyclonal antibody against Crystallin Alpha B (CRYaB).
Host
Rabbit
Reactivity
Mouse
Applications
WB, IHC, IF/ICC
Conjugation
Unconjugated
Crystallin Alpha B (CRYAB) Antibody (Biotin), Abbexa, abx105123
Alpha-crystallin B chain Antibody (Biotin) is a Rabbit Polyclonal antibody against Alpha-crystallin B chain conjugated to Biotin.
Host
Rabbit
Reactivity
Human
Applications
ELISA
Conjugation
Biotin
Crystallin Alpha B (CRYAB) Antibody (FITC), Abbexa, abx106540
Alpha-crystallin B chain Antibody (FITC) is a Rabbit Polyclonal antibody against Alpha-crystallin B chain conjugated to FITC.
Host
Rabbit
Reactivity
Human
Applications
Conjugation
FITC
Crystallin Alpha B (CRYAB) Antibody (HRP), Abbexa, abx107957
Alpha-crystallin B chain Antibody (HRP) is a Rabbit Polyclonal antibody against Alpha-crystallin B chain conjugated to HRP.
Host
Rabbit
Reactivity
Human
Applications
ELISA
Conjugation
HRP
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