Search results for DKC1 antibody
H/ACA Ribonucleoprotein Complex Subunit DKC1 (DKC1) Antibody, Abbexa, abx001537
DKC1 Antibody is a Rabbit Polyclonal antibody against DKC1. This gene is a member of the H/ACA snoRNPs (small nucleolar ribonucleoproteins) gene family. snoRNPs are involved in various aspects of rRNA processing and modification and have been classified into two families: C/D and H/ACA. The H/ACA snoRNPs also include the NOLA1, 2 and 3 proteins. The protein encoded by this gene and the three NOLA proteins localize to the dense fibrillar components of nucleoli and to coiled (Cajal) bodies in the nucleus. Both 18S rRNA production and rRNA pseudouridylation are impaired if any one of the four proteins is depleted. These four H/ACA snoRNP proteins are also components of the telomerase complex. The protein encoded by this gene is related to the Saccharomyces cerevisiae Cbf5p and Drosophila melanogaster Nop60B proteins. The gene lies in a tail-to-tail orientation with the palmitoylated erythrocyte membrane protein gene and is transcribed in a telomere to centromere direction. Both nucleotide substitutions and single trinucleotide repeat polymorphisms have been found in this gene. Mutations in this gene cause X-linked dyskeratosis congenita, a disease resulting in reticulate skin pigmentation, mucosal leukoplakia, nail dystrophy, and progressive bone marrow failure in most cases. Mutations in this gene also cause Hoyeraal-Hreidarsson syndrome, which is a more severe form of dyskeratosis congenita. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008].
Host
Rabbit
Reactivity
Human, Mouse
Applications
IHC, IF/ICC
Conjugation
Unconjugated
H/ACA Ribonucleoprotein Complex Subunit DKC1 (DKC1) Antibody, Abbexa, abx232400
DKC1 Antibody is a Rabbit Polyclonal against DKC1.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB, IHC, IF/ICC
Conjugation
Unconjugated
H/ACA Ribonucleoprotein Complex Subunit DKC1 (DKC1) Antibody, Abbexa, abx329534
DKC1 Antibody is a Rabbit Polyclonal against DKC1.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB, IHC, IF/ICC
Conjugation
Unconjugated
H/ACA Ribonucleoprotein Complex Subunit DKC1 (DKC1) Antibody, Abbexa, abx032535
DKC1 is a member of the H/ACA snoRNPs (small nucleolar ribonucleoproteins) gene family. snoRNPs are involved in various aspects of rRNA processing and modification and have been classified into two families: C/D and H/ACA. The H/ACA snoRNPs also include the NOLA1, 2 and 3 proteins. The protein encoded by this gene and the three NOLA proteins localize to the dense fibrillar components of nucleoli and to coiled (Cajal) bodies in the nucleus. Both 18S rRNA production and rRNA pseudouridylation are impaired if any one of the four proteins is depleted. These four H/ACA snoRNP proteins are also components of the telomerase complex. The protein encoded by this gene is related to the Saccharomyces cerevisiae Cbf5p and Drosophila melanogaster Nop60B proteins. The gene lies in a tail-to-tail orientation with the palmitoylated erythrocyte membrane protein gene and is transcribed in a telomere to centromere direction. Both nucleotide substitutions and single trinucleotide repeat polymorphisms have been found in this gene. Mutations in this gene cause X-linked dyskeratosis congenita, a disease resulting in reticulate skin pigmentation, mucosal leukoplakia, nail dystrophy, and progressive bone marrow failure in most cases.
Host
Rabbit
Reactivity
Human, Mouse
Applications
ELISA, WB, IHC, IF/ICC
Conjugation
Unconjugated
H/ACA Ribonucleoprotein Complex Subunit DKC1 (DKC1) Antibody (HRP), Abbexa, abx315673
DKC1 Antibody (HRP) is a Rabbit Polyclonal against DKC1 conjugated to HRP.
Host
Rabbit
Reactivity
Human
Applications
ELISA
Conjugation
HRP
H/ACA Ribonucleoprotein Complex Subunit DKC1 (DKC1) Antibody (FITC), Abbexa, abx315674
DKC1 Antibody (FITC) is a Rabbit Polyclonal against DKC1 conjugated to FITC.
Host
Rabbit
Reactivity
Human
Applications
Conjugation
FITC
H/ACA Ribonucleoprotein Complex Subunit DKC1 (DKC1) Antibody (Biotin), Abbexa, abx315675
DKC1 Antibody (Biotin) is a Rabbit Polyclonal against DKC1 conjugated to Biotin.
Host
Rabbit
Reactivity
Human
Applications
ELISA
Conjugation
Biotin
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