Search results for DNA-dependent protein kinase catalytic subunit
DNA-Dependent Protein Kinase Catalytic Subunit (PRKDC) Antibody, Abbexa, abx114816
Protein Kinase, Dna-Activated, Catalytic Polypeptide Antibody is a Rabbit Polyclonal antibody against Protein Kinase, Dna-Activated, Catalytic Polypeptide.
Host
Rabbit
Reactivity
Human, Mouse
Applications
ELISA, WB
Conjugation
Unconjugated
DNA-Dependent Protein Kinase Catalytic Subunit (PRKDC) Antibody, Abbexa, abx013061
Rabbit polyclonal antibody against DNA-PK protein. Immunogen region is C-terminal.
Host
Rabbit
Reactivity
Human, Mouse
Applications
ELISA, WB, IHC, IF/ICC
Conjugation
Unconjugated
DNA-Dependent Protein Kinase Catalytic Subunit (PRKDC) Antibody, Abbexa, abx325126
PRKDC Antibody is a Rabbit Polyclonal against PRKDC.
Host
Rabbit
Reactivity
Human, Mouse
Applications
ELISA, IF/ICC
Conjugation
Unconjugated
DNA-Dependent Protein Kinase Catalytic Subunit (PRKDC) Antibody, Abbexa, abx326125
PRKDC Antibody is a Rabbit Polyclonal against PRKDC.
Host
Rabbit
Reactivity
Human, Mouse
Applications
ELISA, WB, IHC, IF/ICC
Conjugation
Unconjugated
DNA-Dependent Protein Kinase Catalytic Subunit (PRKDC) Antibody, Abbexa, abx001229
PRKDC Antibody is a Rabbit Polyclonal antibody against PRKDC. PRKDC, also named as HYRC, HYRC1, DNPK1 and p460, belongs to the PI3/PI4-kinase family. PRKDC is a serine/threonine-protein kinase that acts as a molecular sensor for DNA damage. Involved in DNA nonhomologous end joining (NHEJ), PRKDC is required for double-strand break (DSB) repair and V(D)J recombination. PRKDC must be bound to DNA to express its catalytic properties. It promotes processing of hairpin DNA structures in V(D)J recombination by activation of the hairpin endonuclease artemis (DCLRE1C). It is required to protect and align broken ends of DNA. PRKDC may also act as a scaffold protein to aid the localization of DNA repair proteins to the site of damage. It is found at the ends of chromosomes, suggesting a further role in the maintenance of telomeric stability and the prevention of chromosomal end fusion. It also involved in modulation of transcription. It recognizes the substrate consensus sequence [ST]-Q. PRKDC phosphorylates 'Ser-139' of histone variant H2AX/H2AFX, thereby regulating DNA damage response mechanism. It phosphorylates DCLRE1C, c-Abl/ABL1, histone H1, HSPCA, c-jun/JUN, p53/TP53, PARP1, POU2F1, DHX9, SRF, XRCC1, XRCC1, XRCC4, XRCC5, XRCC6, WRN, c-myc/MYC and RFA2. The antibody recognizes the C-term of PRKDC.
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
DNA-Dependent Protein Kinase Catalytic Subunit (PRKDC) Antibody, Abbexa, abx322980
PRKDC Antibody is a Rabbit Polyclonal against PRKDC.
Host
Rabbit
Reactivity
Human
Applications
ELISA, IHC
Conjugation
Unconjugated
DNA-Dependent Protein Kinase Catalytic Subunit (PRKDC) Antibody, Abbexa, abx325224
PRKDC Antibody is a Rabbit Polyclonal against PRKDC.
Host
Rabbit
Reactivity
Human, Mouse
Applications
ELISA, IHC
Conjugation
Unconjugated
DNA-Dependent Protein Kinase Catalytic Subunit (PRKDC) Antibody, Abbexa, abx322848
PRKDC Antibody is a Rabbit Polyclonal against PRKDC.
Host
Rabbit
Reactivity
Human
Applications
ELISA, IF/ICC
Conjugation
Unconjugated
DNA-Dependent Protein Kinase Catalytic Subunit (PRKDC) Antibody (Biotin), Abbexa, abx315936
PRKDC Antibody (Biotin) is a Rabbit Polyclonal against PRKDC conjugated to Biotin.
Host
Rabbit
Reactivity
Human
Applications
ELISA
Conjugation
Biotin
DNA-Dependent Protein Kinase Catalytic Subunit (PRKDC) Antibody (FITC), Abbexa, abx315935
PRKDC Antibody (FITC) is a Rabbit Polyclonal against PRKDC conjugated to FITC.
Host
Rabbit
Reactivity
Human
Applications
Conjugation
FITC
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