Search results for DNM1L

Dynamin 1 Like Protein (DNM1L) Antibody, Abbexa, abx015842

The protein encoded by this gene is a member of the dynamin superfamily of GTPases.Members of the dynamin-related subfamily, including the S.cerevisiae proteins Dnm1 and Vps1, contain the N-terminal tripartite GTPase domain but do not have the pleckstrin homology or proline-rich domains.This protein establishes mitochondrial morphology through a role in distributing mitochondrial tubules throughout the cytoplasm.The gene has 3 alternatively spliced transcripts encoding different isoforms.These transcripts are alternatively polyadenylated.

Dynamin-1-Like Protein (DNM1L) Antibody, Abbexa, abx013015

Dynamin-1-Like Protein (DNM1L) antibody is a Rabbit polyclonal against Dynamin-1-Like Protein (DNM1L).

Dynamin 1 Like Protein (DNM1L) Antibody, Abbexa, abx126887

DNM1L Antibody is a Rabbit Polyclonal against DNM1L.

Dynamin 1 Like Protein (DNM1L) Antibody, Abbexa, abx224029

DNM1L Antibody is a Mouse Monoclonal against DNM1L.

Dynamin-1-Like Protein (DNM1L) Antibody, Abbexa, abx376716

Dynamin-1-Like Protein (DNM1L) Antibody is a Rabbit polyclonal antibody for the detection of Human Dynamin-1-Like Protein (DNM1L).

Dynamin 1 Like Protein (DNM1L) Antibody, Abbexa, abx303650

DNM1L Antibody is a Rabbit Polyclonal against DNM1L.

Dynamin 1 Like Protein (DNM1L) Antibody, Abbexa, abx002022

DNM1L Antibody is a Rabbit Polyclonal antibody against DNM1L. Dynamin-related protein 1 (DNM1L) is a member of the dynamin superfamily of GTPases. Members of this family have diverse cellular functions including vesicle scission, organelle fission, viral resistance, and intracellular trafficking (reviewed in 1). DNM1L affects mitochondrial morphology and is important in mitochondrial and peroxisomal fission in mammalian cells (2-5). The yeast ortholog of DNM1L clusters into a spiral-shaped structure on the mitochondrial membrane at the site of fission (reviewed in 6), and this structure is likely conserved in mammalian cells (3). The division of the mitochondria, which is required for apoptosis, as well as normal cell growth and development is controlled, in part, by the phosphorylation of DNM1L at Ser616 by Cdk1/cyclin B and at Ser637 by protein kinase A (PKA) (reviewed in 6). When phosphorylated at Ser616, DNM1L stimulates mitochondrial fission during mitosis. Conversely, fission is inhibited when DNM1L is phosphorylated at Ser637 (reviewed in 6). Dephosphorylation at Ser637 by calcineurin reverses this inhibition (7). In addition to phosphorylation, sumoylation of DNM1L is also an enhancer of mitochondrial fission (8). Balancing fission and fusion events is essential for proper mitochondrial function. Research studies have demonstrated mitochondrial defects in a variety of neurodegenerative diseases including Alzheimer’s disease, Parkinson’s disease, and Huntington’s disease (reviewed in 6).

Phospho-DRP1(Ser616) Antibody (YA5812), MedChemexpress, HY-P86120

Phospho-DRP1(Ser616) Antibody (YA5812) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Phospho-DRP1(Ser616).

DRP1 Antibody (YA6305), MedChemexpress, HY-P86613

DRP1 Antibody (YA6305) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to DRP1.

DRP1 (phospho Ser616) antibody, Genetex, GTX05115