Search results for DNMT3L antibody

Anti-DNMT3L Antibody (R3Z99), AntibodySystem, RHN22204

Anti-DNMT3L Antibody (N117/1), AntibodySystem, RHN22201

Anti-DNMT3L Antibody (N117/3), AntibodySystem, RHN22202

Anti-DNMT3L Antibody (N117/9), AntibodySystem, RHN22203

DNA Methyltransferase 3 Like (DNMT3L) Antibody, Abbexa, abx224398

DNMT3L Antibody is a Mouse Monoclonal against DNMT3L.

DNA Methyltransferase 3 Like (DNMT3L) Antibody, Abbexa, abx339104

DNMT3L Antibody is a Rabbit Polyclonal against DNMT3L.

DNA Methyltransferase 3 Like (Dnmt3L) Antibody, Abbexa, abx025810

mDnmt3L (DNA methyltransferase 3L) does not appear to be catalytically active due to loss of the critical active site residues. It may function not directly as a DNA methyltransferase but rather as a regulator of methylation at imprinted loci. It is required specifically for the establishment of genomic imprints but is dispensable for their propagation. It is essential for the de novo methylation of single-copy DNA sequences. The protein is well-express in testis, thymus, ovary, and heart. mDnmt3L, which belongs to the 5-cytosine methyltransferase family, contains 1 ADD-type zinc finger.

DNA Methyltransferase 3 Like (DNMT3L) Antibody, Abbexa, abx122090

Rabbit Polyclonal against the DNMT3L protein.

DNA Methyltransferase 3 Like (Dnmt3L) Antibody, Abbexa, abx025706

CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a nuclear protein with similarity to DNA methyltransferases. This protein is not thought to function as a DNA methyltransferase as it does not contain the amino acid residues necessary for methyltransferase activity. However, this protein does stimulate de novo methylation by DNA cytosine methyltransferase 3 alpha and it is thought to be required for the establishment of maternal genomic imprints. This protein also mediates transcriptional repression through interaction with histone deacetylase 1. Alternative splicing results in two transcript variants. An additional splice variant has been described but its biological validity has not been determined.

DNA Methyltransferase 3 Like (DNMT3L) Antibody, Abbexa, abx028909

CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a nuclear protein with similarity to DNA methyltransferases. This protein is not thought to function as a DNA methyltransferase as it does not contain the amino acid residues necessary for methyltransferase activity. However, this protein does stimulate de novo methylation by DNA cytosine methyltransferase 3 alpha and it is thought to be required for the establishment of maternal genomic imprints. This protein also mediates transcriptional repression through interaction with histone deacetylase 1. Alternative splicing results in two transcript variants. An additional splice variant has been described but its biological validity has not been determined.