Search results for Ectonucleotide Pyrophosphatase/phosphodiesterase 2 (ENPP2) Antibody
Ectonucleotide Pyrophosphatase/phosphodiesterase 2 (ENPP2) Antibody, Abbexa, abx031747
ENPP2 functions as both a phosphodiesterase, which cleaves phosphodiester bonds at the 5' end of oligonucleotides, and a phospholipase, which catalyzes production of lysophosphatidic acid (LPA) in extracellular fluids. LPA evokes growth factor-like responses including stimulation of cell proliferation and chemotaxis. This protein stimulates the motility of tumor cells and has angiogenic properties, and its expression is upregulated in several kinds of carcinomas. The protein is secreted and further processed to make the biologically active form.
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB, FCM
Conjugation
Unconjugated
Ectonucleotide Pyrophosphatase/Phosphodiesterase 2 (ENPP2) Antibody, Abbexa, abx327515
ENPP2 Antibody is a Rabbit Polyclonal against ENPP2.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB
Conjugation
Unconjugated
Ectonucleotide Pyrophosphatase/phosphodiesterase 2 (ENPP2) Antibody, Abbexa, abx240128
Ectonucleotide Pyrophosphatase/phosphodiesterase 2 (ENPP2) Antibody is a Rabbit Polyclonal antibody for the detection of Autotaxin. Hydrolyzes lysophospholipids to produce lysophosphatidic acid (LPA) in extracellular fluids. Major substrate is lysophosphatidylcholine. Also can act on sphingosylphosphphorylcholine producing sphingosine-1-phosphate, a modulator of cell motility. Can hydrolyze, in vitro, bis-pNPP, to some extent pNP-TMP, and barely ATP. Involved in several motility-related processes such as angiogenesis and neurite outgrowth. Acts as an angiogenic factor by stimulating migration of smooth muscle cells and microtubule formation. Stimulates migration of melanoma cells, probably via a pertussis toxin-sensitive G protein. May have a role in induction of parturition. Possible involvement in cell proliferation and adipose tissue development. Tumor cell motility-stimulating factor.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
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