Search results for Estrogen Receptor (ESR1) Antibody
Estrogen Receptor (ESR1) Antibody, Abbexa, abx025242
This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative splicing results in several transcript variants, which differ in their 5' UTRs and use different promoters.
Host
Mouse
Reactivity
Human
Applications
ELISA, WB
Conjugation
Unconjugated
Estrogen Receptor (ESR1) Antibody, Abbexa, abx109764
Estrogen receptor Antibody is a Rabbit Polyclonal antibody against Estrogen receptor.
Host
Rabbit
Reactivity
Human, Rat
Applications
ELISA, WB, IHC, ChIP
Conjugation
Unconjugated
Estrogen Receptor (ESR1) Antibody, Abbexa, abx015850
This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription.The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2.Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone.Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis.
Host
Mouse
Reactivity
Human
Applications
ELISA, WB, IHC, IF/ICC
Conjugation
Unconjugated
Estrogen Receptor (ESR1) Antibody, Abbexa, abx328483
ESR1 Antibody is a Rabbit Polyclonal against ESR1.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
Estrogen Receptor (ESR1) Antibody, Abbexa, abx329758
ESR1 Antibody is a Rabbit Polyclonal against ESR1.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
WB
Conjugation
Unconjugated
Estrogen Receptor (ESR1) Antibody, Abbexa, abx010734
ER (estrogen receptor 1) a member of the steroid receptor superfamily, contains highly conserved DNA binding (DBD) and ligand binding domains (LBD). Through its estrogen-independent and estrogen-dependent activation domains (AF-1 and AF-2, respectively), ER regulates transcription by recruiting coactivator proteins and interacting with general transcriptional machinery. Phosphorylation provides an important mechanism to regulate ER activity. ER is phosphorylated on multiple sites. Serines 104, 106, 118 and 167 are located in the amino-terminal transcription activation function domain AF-1, and phosphorylation of these serines plays an important role in regulating ER activity. Ser118 may be the substrate of the transcription regulatory kinase cdK7. Ser167 may be phosphorylated by p90RSK and Akt. Phosphorylation of Ser167 may confer tamoxifen resistance in breast cancer patients.
Host
Mouse
Reactivity
Human
Applications
ELISA, WB
Conjugation
Unconjugated
Estrogen Receptor (ESR1) Antibody, Abbexa, abx232822
ER Antibody is a Rabbit Polyclonal against ER.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
Estrogen receptor (ESR1) Antibody, Abbexa, abx402520
Estrogen receptor (ESR1) Antibody is a Recombinant Rabbit Monoclonal antibody for the detection of Human ESR1.
Host
Rabbit
Reactivity
Human
Applications
ELISA, IHC
Conjugation
Unconjugated
Estrogen Receptor (ESR1) Antibody, Abbexa, abx325813
ESR1 Antibody is a Rabbit Polyclonal against ESR1.
Host
Rabbit
Reactivity
Human, Mouse
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
Estrogen Receptor (ESR1) Antibody, Abbexa, abx010735
ER alpha is a nuclear hormone receptor and transcription factor. Regulates gene expression and affects cellular proliferation and differentiation in target tissues. Two splice-variant isoforms have been described.
Host
Mouse
Reactivity
Human
Applications
ELISA
Conjugation
Unconjugated
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