Search results for INK4A
p16 INK4A (D7C1M) Rabbit Monoclonal Antibody (Alexa Fluor®488 Conjugate)#32223, Cell Signaling Technology (CST), 32223
p16 INK4A (D7C1M) Rabbit Monoclonal Antibody (Alexa Fluor®488 Conjugate) recognizes endogenous levels of total p16 INK4A protein. This antibody does not cross-react with p15 INK4B. This antibody is not recommended for use in immunohistochemistry.
Host
Rabbit
Reactivity
Human
Applications
Flow Cytometry (Fixed/Permeabilized): 1:50
Conjugation
p16 INK4A (D7C1M) Rabbit Monoclonal Antibody (Alexa Fluor®647 Conjugate)#43161, Cell Signaling Technology (CST), 43161
p16 INK4A (D7C1M) Rabbit Monoclonal Antibody (Alexa Fluor®647 Conjugate) recognizes endogenous levels of total p16 INK4A protein. This antibody conjugate does not cross-react with p15 INK4B. This antibody conjugate is not recommended for use in immunohistochemistry.
Host
Rabbit
Reactivity
Human
Applications
Flow Cytometry (Fixed/Permeabilized): 1:50
Conjugation
p16 INK4A (D7C1M) Rabbit Monoclonal Antibody (SignalFlexTMmFluorTMUV375 Conjugate)#92018, Cell Signaling Technology (CST), 92018
p16 INK4A (D7C1M) Rabbit mAb (SignalFlexTM mFluorTM UV375 Conjugate) recognizes endogenous levels of total p16 INK4A protein. This antibody does not cross-react with p15 INK4B. This antibody is not recommended for use in immunohistochemistry.
Host
Rabbit
Reactivity
Human
Applications
Conjugation
SignalFlexTMmFluorTMUV375 Conjugate
p16 INK4A (D7C1M) Rabbit Monoclonal Antibody (SignalFlexTMAlexa Fluor®350 Conjugate)#23818, Cell Signaling Technology (CST), 23818
p16 INK4A (D7C1M) Rabbit mAb (SignalFlexTM Alexa Fluor®350 Conjugate) recognizes endogenous levels of total p16 INK4A protein. This antibody does not cross-react with p15 INK4B. This antibody is not recommended for use in immunohistochemistry.
Host
Rabbit
Reactivity
Human
Applications
Conjugation
SignalFlexTMAlexa Fluor®350 Conjugate
p16 INK4A (D7C1M) Rabbit Monoclonal Antibody (SignalFlexTMAlexa Fluor®555 Conjugate)#84411, Cell Signaling Technology (CST), 84411
p16 INK4A (D7C1M) Rabbit mAb (SignalFlexTM Alexa Fluor®555 Conjugate) recognizes endogenous levels of total p16 INK4A protein. This antibody does not cross-react with p15 INK4B. This antibody is not recommended for use in immunohistochemistry.
Host
Rabbit
Reactivity
Human
Applications
Conjugation
SignalFlexTMAlexa Fluor®555 Conjugate
p16 INK4A (D7C1M) Rabbit Monoclonal Antibody (SignalFlexTMAlexa Fluor®700 Conjugate)#74405, Cell Signaling Technology (CST), 74405
p16 INK4A (D7C1M) Rabbit mAb (SignalFlexTM Alexa Fluor®700 Conjugate) recognizes endogenous levels of total p16 INK4A protein. This antibody does not cross-react with p15 INK4B. This antibody is not recommended for use in immunohistochemistry.
Host
Rabbit
Reactivity
Human
Applications
Conjugation
SignalFlexTMAlexa Fluor®700 Conjugate
p16 INK4A (D7C1M) Rabbit Monoclonal Antibody (SignalFlexTMmFluorTMRed 780 Conjugate)#25439, Cell Signaling Technology (CST), 25439
p16 INK4A (D7C1M) Rabbit mAb (SignalFlexTM mFluorTM Red 780 Conjugate) recognizes endogenous levels of total p16 INK4A protein. This antibody does not cross-react with p15 INK4B. This antibody is not recommended for use in immunohistochemistry.
Host
Rabbit
Reactivity
Human
Applications
Conjugation
SignalFlexTMmFluorTMRed 780 Conjugate
p16 INK4A (D7C1M) Rabbit Monoclonal Antibody (SignalFlexTMmFluorTMViolet 510 Conjugate)#23380, Cell Signaling Technology (CST), 23380
p16 INK4A (D7C1M) Rabbit mAb (SignalFlexTM mFluorTM Violet 510 Conjugate) recognizes endogenous levels of total p16 INK4A protein. This antibody does not cross-react with p15 INK4B. This antibody is not recommended for use in immunohistochemistry.
Host
Rabbit
Reactivity
Human
Applications
Conjugation
SignalFlexTMmFluorTMViolet 510 Conjugate
hp16-INK4A Antibody, Abbexa, abx030816
This gene generates several transcript variants which differ in their first exons. At least three alternatively spliced variants encoding distinct proteins have been reported, two of which encode structurally related isoforms known to function as inhibitors of CDK4 kinase. The remaining transcript includes an alternate first exon located 20 Kb upstream of the remainder of the gene; this transcript contains an alternate open reading frame (ARF) that specifies a protein which is structurally unrelated to the products of the other variants. This ARF product functions as a stabilizer of the tumor suppressor protein p53 as it can interact with, and sequester, MDM1, a protein responsible for the degradation of p53. In spite of the structural and functional differences, the CDK inhibitor isoforms and the ARF product encoded by this gene, through the regulatory roles of CDK4 and p53 in cell cycle G1 progression, share a common functionality in cell cycle G1 control. This gene is frequently mutated or deleted in a wide variety of tumors, and is known to be an important tumor suppressor gene.
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB
Conjugation
Unconjugated
p16-INK4A (pS140) Antibody, Abbexa, abx031883
p16-INK4A functions as a stabilizer of the tumor suppressor protein p53 as it can interact with, and sequester, MDM1, a protein responsible for the degradation of p53. This protein acts as a negative regulator of the proliferation of normal cells by interacting strongly with CDK4 and CDK6. This inhibits their ability to interact with cyclins D and to phosphorylate the retinoblastoma protein. The gene for this protein is frequently mutated or deleted in a wide variety of tumors, and is known to be an important tumor suppressor gene.
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
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