Search results for Inhibitor of nuclear factor kappa B kinase subunit beta
Inhibitor of Nuclear Factor Kappa-B Kinase Subunit Beta (IKK beta) Antibody, Abbexa, abx025556
NFKB1 (MIM 164011) or NFKB2 (MIM 164012) is bound to REL (MIM 164910), RELA (MIM 164014), or RELB (MIM 604758) to form the NFKB complex. The NFKB complex is inhibited by I-kappa-B proteins (NFKBIA, MIM 164008, or NFKBIB, MIM 604495), which inactivate NF-kappa-B by trapping it in the cytoplasm. Phosphorylation of serine residues on the I-kappa-B proteins by kinases (IKBKA, MIM 600664, or IKBKB) marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF-kappa-B complex. Activated NFKB complex translocates into the nucleus and binds DNA at kappa-B-binding motifs such as 5-prime GGGRNNYYCC 3-prime or 5-prime HGGARNYYCC 3-prime (where H is A, C, or T; R is an A or G purine; and Y is a C or T pyrimidine).
Host
Mouse
Reactivity
Human
Applications
ELISA, WB
Conjugation
Unconjugated
Inhibitor of Nuclear Factor Kappa-B Kinase Subunit Beta / IKKB (IKBKB) Antibody, Abbexa, abx001699
IKBKB Antibody is a Rabbit Polyclonal antibody against IKBKB. The protein encoded by this gene phosphorylates the inhibitor in the inhibitor/NF-kappa-B complex, causing dissociation of the inhibitor and activation of NF-kappa-B. The encoded protein itself is found in a complex of proteins. Several transcript variants, some protein-coding and some not, have been found for this gene.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
WB, IHC
Conjugation
Unconjugated
Inhibitor of Nuclear Factor Kappa-B Kinase Subunit Beta / IKKB (IKBKB) Antibody, Abbexa, abx131197
IkBKb Antibody is a Rabbit Polyclonal against IkBKb.
Host
Rabbit
Reactivity
Mouse
Applications
WB, IHC, IF/ICC
Conjugation
Unconjugated
Inhibitor of Nuclear Factor Kappa-B Kinase Subunit Beta / IKKB (IKBKB) Antibody, Abbexa, abx326413
IKBKB Antibody is a Rabbit Polyclonal against IKBKB.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, IHC
Conjugation
Unconjugated
Inhibitor of Nuclear Factor Kappa-B Kinase Subunit Beta (IKK beta) Antibody, Abbexa, abx033879
This gene encodes a member of the serine/threonine protein kinase family. The encoded protein, a component of a cytokine-activated protein complex that is an inhibitor of the essential transcription factor NF-kappa-B complex, phosphorylates sites that trigger the degradation of the inhibitor via the ubiquination pathway, thereby activating the transcription factor.
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB, IHC, IF/ICC
Conjugation
Unconjugated
Inhibitor of Nuclear Factor Kappa-B Kinase Subunit Beta / IKKB (IKBKB) Antibody, Abbexa, abx113137
Inhibitor Of Kappa Light Polypeptide Gene Enhancer In B-Cells, Kinase Beta Antibody is a Rabbit Polyclonal antibody against Inhibitor Of Kappa Light Polypeptide Gene Enhancer In B-Cells, Kinase Beta.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB
Conjugation
Unconjugated
Inhibitor of Nuclear Factor Kappa-B Kinase Subunit Beta / IKKB (IKBKB) Antibody, Abbexa, abx340128
IKBKB Antibody is a Rabbit Polyclonal against IKBKB.
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
Inhibitor of Nuclear Factor Kappa-B Kinase Subunit Beta / IKKB (IKBKB) Antibody, Abbexa, abx172895
This product is currently in development. The lead time for this product may be several months. Please contact us at [email protected] for an updated lead time before purchasing this product. Inhibitor of Nuclear Factor Kappa-B Kinase Subunit Beta / IKKB (IkBKb) Antibody is a Mouse Monoclonal antibody against Inhibitor of Nuclear Factor Kappa-B Kinase Subunit Beta / IKKB (IkBKb).
Host
Mouse
Reactivity
Human
Applications
WB, IHC, IF/ICC
Conjugation
Unconjugated
Inhibitor of Nuclear Factor Kappa-B Kinase Subunit Beta (IKK beta) Antibody, Abbexa, abx025555
NFKB1 (MIM 164011) or NFKB2 (MIM 164012) is bound to REL (MIM 164910), RELA (MIM 164014), or RELB (MIM 604758) to form the NFKB complex. The NFKB complex is inhibited by I-kappa-B proteins (NFKBIA, MIM 164008, or NFKBIB, MIM 604495), which inactivate NF-kappa-B by trapping it in the cytoplasm. Phosphorylation of serine residues on the I-kappa-B proteins by kinases (IKBKA, MIM 600664, or IKBKB) marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF-kappa-B complex. Activated NFKB complex translocates into the nucleus and binds DNA at kappa-B-binding motifs such as 5-prime GGGRNNYYCC 3-prime or 5-prime HGGARNYYCC 3-prime (where H is A, C, or T; R is an A or G purine; and Y is a C or T pyrimidine).
Host
Mouse
Reactivity
Human
Applications
ELISA, WB
Conjugation
Unconjugated
Inhibitor of Nuclear Factor Kappa-B Kinase Subunit Beta / IKKB (IKBKB) Antibody, Abbexa, abx016029
IKBKB (Inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta, also called IKK2/IKKB), is a member of the IKK complex which is composed of IKK-alpha, IKK-beta, IKK-gamma and IKAP.Phosphorylation of I-Kappa-B on a serine residue by the IKK complex frees NF-kB from I-Kappa-B and marks it for degradation via ubiquination.IKK-beta has been shown to activate NF-kB and phosphorylate IKB-alpha and beta.Phosphorylation of 2 sites at the activation loop of IKK-beta is essential for activation of IKK by TNF and IL1.Once activated, IKK-beta autophosphorylates which in turn decreases IKK activity and prevents prolonged activation of the inflammatory response.Additionally, IKK-beta activity can also be regulated by MEKK-1.
Host
Mouse
Reactivity
Human
Applications
ELISA, IHC
Conjugation
Unconjugated
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