Search results for LC3B Antibody

LC3B Antibody (YA308), MedChemexpress, HY-P80209

LC3B Antibody (YA308) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to LC3B.

LC3B antibody [HL2798], Genetex, GTX639686

LC3B Antibody#2775, Cell Signaling Technology (CST), 2775

LC3B Antibody detects endogenous levels of total LC3B protein. Cross-reactivity may exist with other LC3 isoforms. Stronger reactivity is observed with the type II form of LC3B.

LC3B antibody [N1C3], Genetex, GTX116080

LC3B antibody [5H12], Genetex, GTX60594

LC3B antibody [GT3612], Genetex, GTX632501

Anti-LC3B antibody, Abcam, AB51520

Anti-LC3B antibody (ab51520) is a rabbit polyclonal antibody and is validated for use in Flow Cyt (Intra), ICC/IF, IHC-Fr, WB in human samples. Anti-LC3B antibody (ab51520) has been cited over 448 times in peer reviewed journals and is trusted by the scientific community. Abcam's high quality validation processes ensure Anti-LC3B antibody (ab51520) has high sensitivity and specificity. Anti-LC3B antibody (ab51520) has 18 independent reviews from customers. Anti-LC3B antibody (anti-MAP1LC3B antibody) (ab51520) specifically detects LC3B (UniProt ID: Q9GZQ8; Molecular weight: 14kDa) and is sold in 100 µL selling sizes. LC3B (MAP1LC3B) or Microtubule-associated protein 1 light chain 3 beta is a key marker of autophagy, a process that cancer cells often exploit for survival and growth. Elevated LC3B expression is commonly observed in various solid tumors and is associated with increased tumor proliferation and metastasis. LC3B facilitates the formation of autophagosomes, which help cancer cells manage stress and maintain cellular homeostasis. ab51520 has been shown to work on human malignant brain tumors, breast cancer, leukemia samples, and murine cells. The product formulation changed to include 1% BSA on 17th May 2017. The following lot does not contain BSA and is still in stock GR320876. All future lots will contain 1% BSA.

Anti-LC3B antibody, Abcam, AB63817

Cleaved LC3B Antibody, Abbexa, abx029981

Macroautophagy is the major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane bound autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane bound structure, which then fuse with the lysosome (or vacuole) releasing a single-membrane bound autophagic bodies which are then degraded within the lysosome (or vacuole). MAP1A and MAP1B are microtubule-associated proteins which mediate the physical interactions between microtubules and components of the cytoskeleton. These proteins are involved in formation of autophagosomal vacuoles (autophagosomes). MAP1A and MAP1B each consist of a heavy chain subunit and multiple light chain subunits. MAP1LC3b is one of the light chain subunits and can associate with either MAP1A or MAP1B. The precursor molecule is cleaved by APG4B/ATG4B to form the cytosolic form, LC3-I. This is activated by APG7L/ATG7, transferred to ATG3 and conjugated to phospholipid to form the membrane-bound form, LC3-II.

Anti-LC3B Antibody (R3W31), AntibodySystem, RHJ53201