Search results for MBD1 antibody

Anti-MBD1 Antibody (N361/93), AntibodySystem, RHJ77901

Anti-MBD1 Antibody (N361A/72), AntibodySystem, RHJ77902

Anti-MBD1 Antibody (N361A/91), AntibodySystem, RHJ77903

Anti-MBD1 antibody [EPR3564] - BSA and Azide free, Abcam, AB247676

ab247676 is the carrier-free version of ab108510 . Species reactivity Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information. Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents . What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies . Conjugation ready Our carrier-free antibodies are typically supplied in a PBS-only formulation, purified and free of BSA, sodium azide and glycerol. This conjugation-ready format is designed for use with fluorochromes, metal isotopes, oligonucleotides, and enzymes, which makes them ideal for antibody labelling, functional and cell-based assays, flow-based assays (e.g. mass cytometry) and Multiplex Imaging applications. Use our conjugation kits for antibody conjugates that are ready-to-use in as little as 20 minutes with 1 minute hands-on-time and 100% antibody recovery: available for fluorescent dyes, HRP, biotin and gold. Compatibility This product is compatible with the Maxpar ® Antibody Labeling Kit from Fluidigm, without the need for antibody preparation. Maxpar ® is a trademark of Fluidigm Canada Inc.

Methyl-CpG-binding domain protein 1 (MBD1) Antibody, Abbexa, abx402402

Methyl-CpG-binding domain protein 1 (MBD1) Antibody is a Recombinant Rabbit Monoclonal antibody for the detection of Human MBD1.

Methyl-Cpg-Binding Domain Protein 1 (MBD1) Antibody, Abbexa, abx457392

Methyl-Cpg-Binding Domain Protein 1 (MBD1) Antibody is a Rabbit polyclonal antibody for the detection of Human Methyl-Cpg-Binding Domain Protein 1 (MBD1).

Methyl CpG Binding Domain Protein 1 (MBD1) Antibody, Abbexa, abx037541

Rabbit Polyclonal against the MBD1 protein.

Methyl-CpG Binding Domain Protein 1 (MBD1) Antibody, Abbexa, abx025689

DNA methylation, or the addition of methyl groups to cytosine bases in the dinucleotide CpG, is imperative to proper development and regulates gene expression. The methylation pattern involves the enzymatic processes of methylation and demethylation. The demethylation enzyme was recently found to be a mammalian protein, which exhibits demethylase activity associated to a methyl-CpG-binding domain (MBD) (1). The enzyme is able to revert methylated cytosine bases to cytosines within the particular dinucleotide sequence mdCpdG by catalyzing the cleaving of the methyl group as methanol. MeCP2 and MBD1 (PCM1) are first found to repress transcription by binding specifically to methylated DNA (2). MBD2 and MBD4 (also known as MED1) were later found to colocalize with foci of heavily methylated satellite DNA and believed to mediate the biological functions of the methylation signal. Surprisingly, MBD3 does not bind methylated DNA both in vivo and in vitro. MBD1, MBD2, MBD3, and MBD4 are found to be expressed in somatic tissues, but the expression of MBD1 and MBD2 is reduced or absent in embryonic stem cells, which are known to be deficient in MeCP1 activity. MBD4 have homology to bacterial base excision repair DNA N-glycosylases/lyases (3). In some microsatellite unstable tumors MBD4 is mutated at an exonic polynucleotide tract (4).

Methyl-CpG Binding Domain Protein 1 (MBD1) Antibody, Abbexa, abx333879

MBD1 Antibody is a Rabbit Polyclonal against MBD1.

Methyl CpG Binding Domain Protein 1 (MBD1) Antibody, Abbexa, abx037542

Rabbit Polyclonal against the MBD1 protein.