Search results for NCF4 antibody
Neutrophil Cytosolic Factor 4 (NCF4) Antibody, Abbexa, abx001708
NCF4 Antibody is a Rabbit Polyclonal antibody against NCF4. The protein encoded by this gene is a cytosolic regulatory component of the superoxide-producing phagocyte NADPH-oxidase, a multicomponent enzyme system important for host defense. This protein is preferentially expressed in cells of myeloid lineage. It interacts primarily with neutrophil cytosolic factor 2 (NCF2/p67-phox) to form a complex with neutrophil cytosolic factor 1 (NCF1/p47-phox), which further interacts with the small G protein RAC1 and translocates to the membrane upon cell stimulation. This complex then activates flavocytochrome b, the membrane-integrated catalytic core of the enzyme system. The PX domain of this protein can bind phospholipid products of the PI(3) kinase, which suggests its role in PI(3) kinase-mediated signaling events. The phosphorylation of this protein was found to negatively regulate the enzyme activity. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008].
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
WB
Conjugation
Unconjugated
Neutrophil Cytosolic Factor 4 (NCF4) Antibody, Abbexa, abx235582
NCF4 Antibody is a Rabbit Polyclonal against NCF4.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
Neutrophil Cytosolic Factor 4 (NCF4) Antibody, Abbexa, abx430269
NCF4 Antibody is a Goat Polyclonal antibody against NCF4.
Host
Goat
Reactivity
Human
Applications
P-ELISA, WB, IHC
Conjugation
Unconjugated
Neutrophil Cytosolic Factor 4 (NCF4) Antibody, Abbexa, abx033526
NCF4 is a cytosolic regulatory component of the superoxide-producing phagocyte NADPH-oxidase, a multicomponent enzyme system important for host defense. This protein is preferentially expressed in cells of myeloid lineage. It interacts primarily with neutrophil cytosolic factor 2 (NCF2/p67-phox) to form a complex with neutrophil cytosolic factor 1 (NCF1/p47-phox), which further interacts with the small G protein RAC1 and translocates to the membrane upon cell stimulation. This complex then activates flavocytochrome b, the membrane-integrated catalytic core of the enzyme system. The PX domain of this protein can bind phospholipid products of the PI (3) kinase, which suggests its role in PI (3) kinase-mediated signaling events. The phosphorylation of this protein was found to negatively regulate the enzyme activity.
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB, IHC, FCM
Conjugation
Unconjugated
Neutrophil cytosol factor 4 (NCF4) Antibody (HRP), Abbexa, abx346063
Neutrophil cytosol factor 4 (NCF4) Antibody (HRP) is a Rabbit Polyclonal antibody conjugated to HRP for the detection of Human NCF4.
Host
Rabbit
Reactivity
Human
Applications
ELISA
Conjugation
HRP
Neutrophil cytosol factor 4 (NCF4) Antibody (Biotin), Abbexa, abx346065
Neutrophil cytosol factor 4 (NCF4) Antibody (Biotin) is a Rabbit Polyclonal antibody conjugated to Biotin for the detection of Human NCF4.
Host
Rabbit
Reactivity
Human
Applications
ELISA
Conjugation
Biotin
Neutrophil cytosol factor 4 (NCF4) Antibody (FITC), Abbexa, abx346064
Neutrophil cytosol factor 4 (NCF4) Antibody (FITC) is a Rabbit Polyclonal antibody conjugated to FITC for the detection of Human NCF4.
Host
Rabbit
Reactivity
Human
Applications
Conjugation
FITC
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