Search results for O-6-methylguanine-DNA methyltransferase
O-6-Methylguanine DNA Methyltransferase (MGMT) Antibody, Abbexa, abx173881
This product is currently in development. The lead time for this product may be several months. Please contact us at [email protected] for an updated lead time before purchasing this product. O-6-Methylguanine DNA Methyltransferase (MGMT) Antibody is a Mouse Monoclonal antibody against O-6-Methylguanine DNA Methyltransferase (MGMT).
Host
Mouse
Reactivity
Human
Applications
WB, IHC, IF/ICC
Conjugation
Unconjugated
O-6-Methylguanine DNA Methyltransferase (MGMT) Antibody, Abbexa, abx000535
MGMT Antibody is a Rabbit Polyclonal antibody against MGMT. MGMT is the primary vehicle for cellular removal of alkyl lesions from the O-6 position of guanine and the O-4 position of thymine. While key to the maintenance of genomic integrity, MGMT also removes damage induced by alkylating chemotherapies, inhibiting the efficacy of cancer treatment [PMID:23065697].MGMT is the primary mechanism for the removal of alkylation damage from the O-6 position of guanine [PMID: 17482892]. The O-6 position of guanine is one of several positions in DNA bases to which alkyl groups are attached in SN1 alkylation reactions, and this repair has been well-characterized in mammalian cells and via MGMT homologs in bacteria and Archaea.[PMID: 10767620].
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB
Conjugation
Unconjugated
O-6-Methylguanine DNA Methyltransferase (MGMT) Antibody, Abbexa, abx027079
MGMT is involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB, FCM
Conjugation
Unconjugated
O-6-Methylguanine DNA Methyltransferase (MGMT) Antibody, Abbexa, abx034911
Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
Host
Mouse
Reactivity
Human
Applications
ELISA, WB, IHC, IF/ICC
Conjugation
Unconjugated
O-6-Methylguanine DNA Methyltransferase (MGMT) Antibody, Abbexa, abx129084
O-6-Methylguanine DNA Methyltransferase Antibody is a Rabbit Polyclonal against O-6-Methylguanine DNA Methyltransferase.
Host
Rabbit
Reactivity
Human
Applications
WB, IHC, IF/ICC
Conjugation
Unconjugated
O-6-Methylguanine DNA Methyltransferase (MGMT) Antibody, Abbexa, abx147078
O-6-Methylguanine DNA Methyltransferase (MGMT) Antibody is a Rabbit Polyclonal antibody for the detection of MGMT. Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
Host
Rabbit
Reactivity
Human
Applications
ELISA, IHC
Conjugation
Unconjugated
O-6-Methylguanine DNA Methyltransferase (MGMT) Antibody, Abbexa, abx224153
MGMT Antibody is a Mouse Monoclonal against MGMT.
Host
Mouse
Reactivity
Human
Applications
ELISA
Conjugation
O-6-Methylguanine DNA Methyltransferase (MGMT) Antibody (FITC), Abbexa, abx107078
Methylated-DNA--protein-cysteine methyltransferase Antibody (FITC) is a Rabbit Polyclonal antibody against Methylated-DNA--protein-cysteine methyltransferase conjugated to FITC.
Host
Rabbit
Reactivity
Human
Applications
Conjugation
FITC
O-6-Methylguanine DNA Methyltransferase (MGMT) Antibody (Biotin), Abbexa, abx105661
Methylated-DNA--protein-cysteine methyltransferase Antibody (Biotin) is a Rabbit Polyclonal antibody against Methylated-DNA--protein-cysteine methyltransferase conjugated to Biotin.
Host
Rabbit
Reactivity
Human
Applications
ELISA
Conjugation
Biotin
O-6-Methylguanine DNA Methyltransferase (MGMT) Antibody (HRP), Abbexa, abx108499
Methylated-DNA--protein-cysteine methyltransferase Antibody (HRP) is a Rabbit Polyclonal antibody against Methylated-DNA--protein-cysteine methyltransferase conjugated to HRP.
Host
Rabbit
Reactivity
Human
Applications
ELISA
Conjugation
HRP
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