Search results for Paired Box Protein Pax-5 (PAX5) Antibody
Paired Box Protein Pax-5 (PAX5) Antibody, Abbexa, abx012139
This gene encodes the B-cell lineage specific activator protein that is expressed at early, but not late stages of B-cell differentiation. Its expression has also been detected in developing CNS and testis and so the encoded protein may also play a role in neural development and spermatogenesis. This gene is located at 9p13, which is involved in t (9;14) (p13;q32) translocations recurring in small lymphocytic lymphomas of the plasmacytoid subtype, and in derived large-cell lymphomas. This translocation brings the potent E-mu enhancer of the IgH gene into close proximity of the PAX5 promoter, suggesting that the deregulation of transcription of this gene contributes to the pathogenesis of these lymphomas. Alternatively spliced transcript variants encoding different isoforms have been described but their biological validity has not been determined. References 1.Cancer Res. 2011 Dec 15;71 (24):7345-50. 2.Am J Clin Pathol. 2010 Jan;133 (1):41-8. Related Products.
Host
Mouse
Reactivity
Human
Applications
ELISA, WB
Conjugation
Unconjugated
Paired Box Protein Pax-5 (PAX5) Antibody, Abbexa, abx338608
PAX5 Antibody is a Rabbit Polyclonal against PAX5.
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB, IF/ICC
Conjugation
Unconjugated
Paired Box Protein Pax-5 (PAX5) Antibody, Abbexa, abx212348
PAX5 Antibody is a Rabbit Polyclonal against PAX5.
Host
Rabbit
Reactivity
Human, Mouse
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
Paired Box Protein Pax-5 (PAX5) Antibody, Abbexa, abx026399
This gene encodes a member of the paired box (PAX) family of transcription factors. The central feature of this gene family is a novel, highly conserved DNA-binding motif, known as the paired box. PAX proteins are important regulators in early development, and alterations in the expression of their genes are thought to contribute to neoplastic transformation. This gene encodes the B-cell lineage specific activator protein that is expressed at early, but not late stages of B-cell differentiation. Its expression has also been detected in developing CNS and testis and so the encoded protein may also play a role in neural development and spermatogenesis. This gene is located at 9p13, which is involved in t (9;14) (p13;q32) translocations recurring in small lymphocytic lymphomas of the plasmacytoid subtype, and in derived large-cell lymphomas. This translocation brings the potent E-mu enhancer of the IgH gene into close proximity of the PAX5 promoter, suggesting that the deregulation of transcription of this gene contributes to the pathogenesis of these lymphomas. Alternatively spliced transcript variants encoding different isoforms have been described but their biological validity has not been determined.
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB, IHC, FCM
Conjugation
Unconjugated
Paired Box Protein Pax-5 (PAX5) Antibody (HRP), Abbexa, abx336916
PAX5 Antibody (HRP) is a Rabbit Polyclonal against PAX5.
Host
Rabbit
Reactivity
Human
Applications
ELISA
Conjugation
HRP
Paired Box Protein Pax-5 (PAX5) Antibody (PE), Abbexa, abx347454
Paired Box Protein Pax-5 (PAX5) Antibody (PE) is a Rat monoclonal antibody against PAX5.
Host
Rat
Reactivity
Human, Mouse
Applications
FCM
Conjugation
PE
Paired Box Protein Pax-5 (PAX5) Antibody (Biotin), Abbexa, abx336918
PAX5 Antibody (Biotin) is a Rabbit Polyclonal against PAX5.
Host
Rabbit
Reactivity
Human
Applications
ELISA
Conjugation
Biotin
Paired Box Protein Pax-5 (PAX5) Antibody (FITC), Abbexa, abx336917
PAX5 Antibody (FITC) is a Rabbit Polyclonal against PAX5.
Host
Rabbit
Reactivity
Human
Applications
Conjugation
FITC
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