Search results for Sialic Acid Binding Ig Like Lectin 7 (SIGLEC7) Antibody
Sialic Acid Binding Ig Like Lectin 7 (SIGLEC7) Antibody, Abbexa, abx025088
SIGLECs are cell surface proteins of the Ig superfamily. Most SIGLECs have 1 or more cytoplasmic immune receptor tyrosine-based inhibitory motifs, or ITIMs. A large subgroup of SIGLECs share high homology with SIGLEC3 (CD33) and are localized to 19q13.4. The cDNA for the SLG gene encodes 2 variants, SLG-long (SLGL) and SLG-short (SLGS). The 595-amino acid SLGL protein contains a signal peptide and 2 V-set N-terminal Ig-like domains. The 477-amino acid SLGS protein has a weak signal sequence and, like most SIGLEC3-like SIGLECs, has only 1 V-set N-terminal Ig-like domain. Both variants contain 2 C2-set N-terminal Ig-like domains, a transmembrane domain, and a cytoplasmic tail with a putative ITIM and a putative SLAM-like tyrosine-based motif. The conserved arginine residue thought to be essential for sialic acid binding in other SIGLECs is replaced by a glutamine in SLGS and by a cysteine in SLGL. RT-PCR analysis detected high expression of both variants in spleen and small intestine, and SLGS was highly expressed in adrenal gland and SLGL was highly expressed in bone marrow.
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
Sialic Acid Binding Ig Like Lectin 7 (SIGLEC7) Antibody, Abbexa, abx403678
Human Sialic Acid Binding Ig Like Lectin 7 (SIGLEC7) Antibody is a Mouse monoclonal against Sialic Acid Binding Ig Like Lectin 7 (SIGLEC7).
Host
Mouse
Reactivity
Human
Applications
WB, IHC, IF/ICC
Conjugation
Unconjugated
Sialic Acid Binding Ig Like Lectin 7 (SIGLEC7) Antibody, Abbexa, abx104097
Polyclonal Antibody to Sialic Acid Binding Ig Like Lectin 7 (SIGLEC7).
Host
Rabbit
Reactivity
Human
Applications
WB, IHC, IF/ICC
Conjugation
Unconjugated
Sialic Acid Binding Ig Like Lectin 7 (SIGLEC7) Antibody, Abbexa, abx339386
SIGLEC7 Antibody is a Rabbit Polyclonal against SIGLEC7.
Host
Rabbit
Reactivity
Human
Applications
ELISA, IHC
Conjugation
Unconjugated
Sialic Acid Binding Ig Like Lectin 7 (SIGLEC7) Antibody, Abbexa, abx025089
SIGLECs are cell surface proteins of the Ig superfamily. Most SIGLECs have 1 or more cytoplasmic immune receptor tyrosine-based inhibitory motifs, or ITIMs. A large subgroup of SIGLECs share high homology with SIGLEC3 (CD33) and are localized to 19q13.4. The cDNA for the SLG gene encodes 2 variants, SLG-long (SLGL) and SLG-short (SLGS). The 595-amino acid SLGL protein contains a signal peptide and 2 V-set N-terminal Ig-like domains. The 477-amino acid SLGS protein has a weak signal sequence and, like most SIGLEC3-like SIGLECs, has only 1 V-set N-terminal Ig-like domain. Both variants contain 2 C2-set N-terminal Ig-like domains, a transmembrane domain, and a cytoplasmic tail with a putative ITIM and a putative SLAM-like tyrosine-based motif. The conserved arginine residue thought to be essential for sialic acid binding in other SIGLECs is replaced by a glutamine in SLGS and by a cysteine in SLGL. RT-PCR analysis detected high expression of both variants in spleen and small intestine, and SLGS was highly expressed in adrenal gland and SLGL was highly expressed in bone marrow.
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
Sialic Acid Binding Ig Like Lectin 7 (SIGLEC7) Antibody, Abbexa, abx403679
Human Sialic Acid Binding Ig Like Lectin 7 (SIGLEC7) Antibody is a Mouse monoclonal against Sialic Acid Binding Ig Like Lectin 7 (SIGLEC7).
Host
Mouse
Reactivity
Human
Applications
WB, IHC, IF/ICC
Conjugation
Unconjugated
Sialic Acid Binding Ig Like Lectin 7 (SIGLEC7) Antibody, Abbexa, abx318263
SIGLEC7 Antibody is a Rabbit Polyclonal against SIGLEC7.
Host
Rabbit
Reactivity
Human, Mouse
Applications
ELISA, WB, IHC, IF/ICC
Conjugation
Unconjugated
Sialic Acid Binding Ig Like Lectin 7 (SIGLEC7) Antibody, Abbexa, abx404787
Human Sialic Acid Binding Ig Like Lectin 7 (SIGLEC7) Antibody is a Rabbit polyclonal against Sialic Acid Binding Ig Like Lectin 7 (SIGLEC7).
Host
Rabbit
Reactivity
Human
Applications
WB, IHC, IF/ICC
Conjugation
Unconjugated
Sialic Acid-Binding Ig-Like Lectin 7 (SIGLEC7) Antibody, Abbexa, abx457497
Sialic Acid-Binding Ig-Like Lectin 7 (SIGLEC7) Antibody is a Rabbit polyclonal antibody for the detection of Human Sialic Acid-Binding Ig-Like Lectin 7 (SIGLEC7).
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
Sialic Acid Binding Ig Like Lectin 7 (SIGLEC7) Antibody, Abbexa, abx211383
SIGLEC7 Antibody is a Rabbit Polyclonal against SIGLEC7.
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB
Conjugation
Unconjugated
Please provide the required information below so that we can quickly source your products.