Search results for Tyrosine-protein kinase ZAP-70 (ZAP70) Antibody
Tyrosine-Protein Kinase ZAP-70 (ZAP70) Antibody, Abbexa, abx016023
ZAP70 (zeta-chain associated protein kinase), a 70 kDa member of the SYK tyrosine kinase family, plays a central role in lymphocyte activation and development, and is implicated in several immune disorders.ZAP70 controls TCR (T-cell antigen receptor)-linked signal transduction pathways.Its key role in thymocytes development and mature T lymphocytes activation has been illustrated by the characterization of several human immunodeficiencies presenting with mutations in the ZAP70 gene.ZAP70 is also expressed in several types of B-cell neoplasm and is easily detected by immunohistochemistry, providing a useful prognostic marker in patients with chronic lymphocytic leukaemia.
Host
Mouse
Reactivity
Human
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
Tyrosine-protein kinase ZAP-70 (ZAP70) Antibody, Abbexa, abx344861
Tyrosine-protein kinase ZAP-70 (ZAP70) Antibody is a Rabbit Polyclonal antibody for the detection of Mouse, Human Zap70.
Host
Rabbit
Reactivity
Human, Mouse
Applications
ELISA, WB, IF/ICC
Conjugation
Unconjugated
Tyrosine-Protein Kinase ZAP-70 (ZAP70) Antibody, Abbexa, abx025459
This gene encodes an enzyme belonging to the protein tyrosine kinase family, and it plays a role in T-cell development and lymphocyte activation. This enzyme, which is phosphorylated on tyrosine residues upon T-cell antigen receptor (TCR) stimulation, functions in the initial step of TCR-mediated signal transduction in combination with the Src family kinases, Lck and Fyn. This enzyme is also essential for thymocyte development. Mutations in this gene cause selective T-cell defect, a severe combined immunodeficiency disease characterized by a selective absence of CD8-positive T-cells. Two transcript variants that encode different isoforms have been found for this gene. This antibody is supplied as crude ascites.
Host
Mouse
Reactivity
Human
Applications
ELISA, WB
Conjugation
Unconjugated
Tyrosine-Protein Kinase ZAP-70 (ZAP70) Antibody (FITC), Abbexa, abx411157
Tyrosine-Protein Kinase ZAP-70 (ZAP70) Antibody (FITC) is a Mouse Monoclonal antibody against Tyrosine-Protein Kinase ZAP-70 (ZAP70).
Host
Mouse
Reactivity
Human
Applications
FCM
Conjugation
FITC
Tyrosine-protein kinase ZAP-70 (ZAP70) Antibody (HRP), Abbexa, abx344862
Tyrosine-protein kinase ZAP-70 (ZAP70) Antibody (HRP) is a Rabbit Polyclonal antibody conjugated to HRP for the detection of Mouse Zap70.
Host
Rabbit
Reactivity
Mouse
Applications
ELISA
Conjugation
HRP
Tyrosine-protein kinase ZAP-70 (ZAP70) Antibody (Biotin), Abbexa, abx344864
Tyrosine-protein kinase ZAP-70 (ZAP70) Antibody (Biotin) is a Rabbit Polyclonal antibody conjugated to Biotin for the detection of Mouse Zap70.
Host
Rabbit
Reactivity
Mouse
Applications
ELISA
Conjugation
Biotin
Tyrosine-protein kinase ZAP-70 (ZAP70) Antibody (FITC), Abbexa, abx344863
Tyrosine-protein kinase ZAP-70 (ZAP70) Antibody (FITC) is a Rabbit Polyclonal antibody conjugated to FITC for the detection of Mouse Zap70.
Host
Rabbit
Reactivity
Mouse
Applications
Conjugation
FITC
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