Search results for furin

Furin (FURIN) Antibody, Abbexa, abx240217
Furin (FURIN) Antibody is a Rabbit Polyclonal antibody for the detection of FURIN. This gene encodes a member of the subtilisin-like proprotein convertase family, which includes proteases that process protein and peptide precursors trafficking through regulated or constitutive branches of the secretory pathway. It encodes a type 1 membrane bound protease that is expressed in many tissues, including neuroendocrine, liver, gut, and brain. The encoded protein undergoes an initial autocatalytic processing event in the ER and then sorts to the trans-Golgi network through endosomes where a second autocatalytic event takes place and the catalytic activity is acquired. The product of this gene is one of the seven basic amino acid-specific members which cleave their substrates at single or paired basic residues. Some of its substrates include proparathyroid hormone, transforming growth factor beta 1 precursor, proalbumin, pro-beta-secretase, membrane type-1 matrix metalloproteinase, beta subunit of pro-nerve growth factor and von Willebrand factor. It is also thought to be one of the proteases responsible for the activation of HIV envelope glycoproteins gp160 and gp140 and may play a role in tumor progression. This gene is located in close proximity to family member proprotein convertase subtilisin/kexin type 6 and upstream of the FES oncogene. Alternative splicing results in multiple transcript variants.
Host
Rabbit
Reactivity
Human
Applications
ELISA, IHC
Conjugation
Unconjugated

Furin (FURIN) Antibody, Abbexa, abx233241
FURIN Antibody is a Rabbit Polyclonal against FURIN.
Host
Rabbit
Reactivity
Human, Mouse
Applications
ELISA, WB, IHC
Conjugation
Unconjugated

Furin (FURIN) Antibody, Abbexa, abx461437
Furin (FURIN) Antibody is a monoclonal Nanobody expressed in CHO cells for the detection of Human FURIN.
Host
CHO cells
Reactivity
Human
Applications
ELISA
Conjugation
Unconjugated

Furin (FURIN) Antibody, Abbexa, abx376349
Furin (FURIN) Antibody is a Rabbit Polyclonal antibody against Furin (FURIN).
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB, IHC, IF/ICC
Conjugation
Unconjugated

Furin (FURIN) Antibody, Abbexa, abx006007
FURIN Antibody is a Rabbit Polyclonal Antibody against FURIN.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
WB
Conjugation
Unconjugated

Furin (FURIN) Antibody, Abbexa, abx433687
Furin (FURIN) Antibody is a Goat Polyclonal against Furin (FURIN).
Host
Goat
Reactivity
Human
Applications
P-ELISA, IHC
Conjugation
Unconjugated

Furin (FURIN) Antibody, Abbexa, abx430533
FURIN Antibody is a Goat Polyclonal antibody against FURIN.
Host
Goat
Reactivity
Human
Applications
P-ELISA, IF/ICC
Conjugation
Unconjugated

Furin (FURIN) Antibody, Abbexa, abx100008
Polyclonal Antibody to Furin (FUR).
Host
Rabbit
Reactivity
Human
Applications
WB, IHC, IF/ICC
Conjugation
Unconjugated

Furin (FURIN) Antibody, Abbexa, abx461436
Furin (FURIN) Antibody is a monoclonal Nanobody expressed in CHO cells for the detection of Human FURIN.
Host
CHO cells
Reactivity
Human
Applications
ELISA, IP, SPR
Conjugation
Unconjugated

Furin (FURIN) Antibody, Abbexa, abx402206
Furin (FURIN) Antibody is a Recombinant Rabbit Monoclonal antibody for the detection of Human FURIN.
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
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