Search results for histone deacetylase A
Histone Deacetylase 5 (HDAC5) Antibody, Abbexa, abx113035
Histone Deacetylase 5 Antibody is a Rabbit Polyclonal antibody against Histone Deacetylase 5.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
Histone Deacetylase 1 (HDAC1) Antibody, Abbexa, abx031187
This product is currently in development. The lead time for this product may be several months. Please contact us at [email protected] for an updated lead time before purchasing this product. This product is currently in development. The lead time for this product may be several months. Please contact us at [email protected] for an updated lead time before purchasing this product. Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis.
Host
Rabbit
Reactivity
Human, Rat
Applications
ELISA, WB
Conjugation
Unconjugated
Histone Deacetylase 5 (HDAC5) Antibody, Abbexa, abx312783
HDAC5 Antibody is a Rabbit Polyclonal against HDAC5.
Host
Rabbit
Reactivity
Human
Applications
ELISA, IHC, IF/ICC
Conjugation
Unconjugated
Histone Deacetylase 7 (HDAC7) Antibody, Abbexa, abx026075
Histone deacetylase (HDAC) and histone acetyltransferase (HAT) are enzymes that regulate transcription by selectively deacetylating or acetylating the eta-amino groups of lysines located near the amino termini of core histone proteins (1). Eight members of HDAC family have been identified in the past several years (2, 3). These HDAC family members are divided into two classes, I and II. Class I of the HDAC family comprises four members, HDAC-1, 2, 3, and 8, each of which contains a deacetylase domain exhibiting from 45 to 93% identity in amino acid sequence. Class II of the HDAC family comprises HDAC-4, 5, 6, and 7, the molecular weights of which are all about two-fold larger than those of the class I members, and the deacetylase domains are present within the C-terminal regions, except that HDAC-6 contains two copies of the domain, one within each of the N-terminal and C-terminal regions. Human HDAC-1, 2 and 3 were expressed in various tissues, but the others (HDAC-4, 5, 6, and 7) showed tissue-specific expression patterns (3). These results suggested that each member of the HDAC family exhibits a different, individual substrate specificity and function in vivo.
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB
Conjugation
Unconjugated
Histone Deacetylase 7 (HDAC7) Antibody, Abbexa, abx213547
HDAC7 Antibody is a Rabbit Polyclonal against HDAC7.
Host
Rabbit
Reactivity
Human, Mouse
Applications
ELISA, WB
Conjugation
Unconjugated
Histone Deacetylase 2 (HDAC2) Antibody, Abbexa, abx224177
HDAC2 Antibody is a Mouse Monoclonal against HDAC2.
Host
Mouse
Reactivity
Human
Applications
ELISA
Conjugation
Histone Deacetylase 2 (HDAC2) Antibody, Abbexa, abx034502
This gene product belongs to the histone deacetylase family. Histone deacetylases act via the formation of large multiprotein complexes, and are responsible for the deacetylation of lysine residues at the N-terminal regions of core histones (H2A, H2B, H3 and H4). This protein forms transcriptional repressor complexes by associating with many different proteins, including YY1, a mammalian zinc-finger transcription factor. Thus, it plays an important role in transcriptional regulation, cell cycle progression and developmental events.
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB, IHC, IF/ICC, FCM
Conjugation
Unconjugated
Histone Deacetylase 6 (HDAC6) Antibody, Abbexa, abx140616
Histone Deacetylase 6 (HDAC6) Antibody is a Mouse Monoclonal Antibody against Histone Deacetylase 6 (HDAC6).
Host
Mouse
Reactivity
Human
Applications
ELISA, WB, IF/ICC, FCM, IP
Conjugation
Unconjugated
Histone Deacetylase 1 (HDAC1) Antibody, Abbexa, abx214669
HDAC1 Antibody is a Rabbit Polyclonal against HDAC1.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
Histone Deacetylase 1 (HDAC1) Antibody, Abbexa, abx132624
Histone Deacetylase 1 (HDAC1) Antibody is a Mouse Monoclonal antibody for the detection of Histone Deacetylase 1 (HDAC1).
Host
Mouse
Reactivity
Human
Applications
WB, IHC, IF/ICC
Conjugation
Unconjugated
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