Search results for insulin like growth factor 1 receptor
Insulin-Like Growth Factor 1 Receptor (IGF1R) Antibody, Abbexa, abx461427
Insulin-Like Growth Factor 1 Receptor (IGF1R) Antibody is a monoclonal Nanobody expressed in CHO cells for the detection of Human IGF1R.
Host
CHO cells
Reactivity
Human
Applications
ELISA, FCM, SPR
Conjugation
Unconjugated
Insulin Like Growth Factor 1 Receptor (IGF1R) Antibody, Abbexa, abx033572
The IGF1R receptor binds insulin-like growth factor with a high affinity and plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. The protein possess tyrosine kinase activity.
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
Insulin-Like Growth Factor 1 Receptor (IGF1R) Antibody, Abbexa, abx421242
Insulin-Like Growth Factor 1 Receptor (IGF1R) Antibody is a Human Monoclonal antibody for the detection of Insulin-Like Growth Factor 1 Receptor (IGF1R) in Human samples.
Host
Human
Reactivity
Human
Applications
FCM
Conjugation
Unconjugated
Insulin-like growth factor 1 receptor (IGF1R) Antibody, Abbexa, abx349924
Insulin-like growth factor 1 receptor (IGF1R) Antibody is a Recombinant Mouse Monoclonal antibody for the detection of Human IGF1R.
Host
Mouse
Reactivity
Human
Applications
ELISA, FCM
Conjugation
Unconjugated
Insulin Like Growth Factor 1 Receptor (IGF1R) Antibody, Abbexa, abx328731
IGF1R Antibody is a Rabbit Polyclonal against IGF1R.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
Insulin Like Growth Factor 1 Receptor (IGF1R) Antibody, Abbexa, abx016028
IGF1R (insulin-like growth factor 1 receptor), a transmembrane receptor tyrosine kinase, is widely expressed in many cell types within fetal and postnatal tissues, and in many cell lines.Upon binding to its ligands, IGF-I and IGF-II, receptor autophosphorylation occurs.The triple tyrosine cluster within the kinase domain (Tyr1131, Tyr1135 and Tyr1136) is the earliest major site of autophosphorylation.Phosphorylation of these three tyrosine residues is necessary for kinase activation.Insulin receptors (IRs) share significant similarity with IGF1 receptors in both structure and function,including an equivalent triple tyrosine cluster within the activation loop of the kinase domain (Tyr1146, Tyr1150 and Tyr1151).Tyrosine autophosphorylation of insulin receptor is one of the earliest cellular responses to insulin stimulation.Autophosphorylation begins with phosphorylation of Tyr1146 and either Tyr1150 or Tyr1151.Full kinase activation requires the triple tyrosine phosphorylation.
Host
Mouse
Reactivity
Human
Applications
ELISA, IHC
Conjugation
Unconjugated
Insulin Like Growth Factor 1 Receptor (IGF1R) Antibody, Abbexa, abx327081
IGF1R Antibody is a Rabbit Polyclonal against IGF1R.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB
Conjugation
Unconjugated
Insulin Like Growth Factor 1 Receptor (IGF1R) Antibody, Abbexa, abx403596
Human Insulin Like Growth Factor 1 Receptor (IGF1R) Antibody is a Mouse monoclonal against Insulin Like Growth Factor 1 Receptor (IGF1R).
Host
Mouse
Reactivity
Human
Applications
WB, IHC, IF/ICC
Conjugation
Unconjugated
Insulin Like Growth Factor 1 Receptor (IGF1R) Antibody, Abbexa, abx113163
Insulin Like Growth Factor 1 Receptor (IGF1R) Antibody is a Rabbit Polyclonal antibody against Insulin Like Growth Factor 1 Receptor (IGF1R).
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB, IP
Conjugation
Unconjugated
Insulin Like Growth Factor 1 Receptor (IGF1R) Antibody (FITC), Abbexa, abx306438
IGF1R Antibody (FITC) is a Rabbit Polyclonal against IGF1R conjugated to FITC.
Host
Rabbit
Reactivity
Human
Applications
Conjugation
FITC
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