Search results for tyrosine kinase 2
Ptk2 Protein Tyrosine Kinase 2 Antibody, Abbexa, abx114917
Ptk2 Protein Tyrosine Kinase 2 Antibody is a Rabbit Polyclonal antibody against Ptk2 Protein Tyrosine Kinase 2.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
Tyrosine Kinase 2 (TYK2) Antibody (Biotin), Abbexa, abx317259
TYK2 Antibody (Biotin) is a Rabbit Polyclonal against TYK2 conjugated to Biotin.
Host
Rabbit
Reactivity
Human
Applications
ELISA
Conjugation
Biotin
Lemur Tyrosine Kinase 2 (LMTK2) Antibody, Abbexa, abx324866
LMTK2 Antibody is a Rabbit Polyclonal against LMTK2.
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB, IHC, IF/ICC
Conjugation
Unconjugated
Lemur Tyrosine Kinase 2 (LMTK2) Antibody, Abbexa, abx013688
Rabbit polyclonal antibody against LMTK2 protein. Immunogen region is Internal.
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB, IHC, IF/ICC
Conjugation
Unconjugated
Tyrosine Kinase 2 (TYK2) Antibody (FITC), Abbexa, abx317258
TYK2 Antibody (FITC) is a Rabbit Polyclonal against TYK2 conjugated to FITC.
Host
Rabbit
Reactivity
Human
Applications
Conjugation
FITC
Tyrosine Kinase 2 (TYK2) Antibody (HRP), Abbexa, abx317257
TYK2 Antibody (HRP) is a Rabbit Polyclonal against TYK2 conjugated to HRP.
Host
Rabbit
Reactivity
Human
Applications
ELISA
Conjugation
HRP
Lemur Tyrosine Kinase 2 (LMTK2) Antibody, Abbexa, abx033196
Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The tyrosine kinase (TK) group is mainly involved in the regulation of cell-cell interactions such as differentiation, adhesion, motility and death. There are currently about 90 TK genes sequenced, 58 are of receptor protein TK (e.g. EGFR, EPH, FGFR, PDGFR, TRK, and VEGFR families), and 32 of cytosolic TK (e.g. ABL, FAK, JAK, and SRC families).
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
Lemur Tyrosine Kinase 2 (LMTK2) Antibody, Abbexa, abx431756
LMTK2 Antibody is a Goat Polyclonal antibody against LMTK2.
Host
Goat
Reactivity
Human
Applications
P-ELISA, WB
Conjugation
Unconjugated
Protein-Tyrosine Kinase 2-Beta (PYK2) Antibody, Abbexa, abx236980
PYK2 Antibody is a Rabbit Polyclonal against PYK2.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
PTK2 Protein Tyrosine Kinase 2 (FAK) Antibody, Abbexa, abx015852
This gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents.The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies.Activation of this gene may be an important early step in cell growth and intracellular signal transduction pathways triggered in response to certain neural peptides or to cell interactions with the extracellular matrix.At least four transcript variants encoding four different isoforms have been found for this gene, but the full-length natures of only two of them have been determined.Tissue specificity: Expressed in all organs tested, in lymphoid cell lines, but most abundantly in brain.RD: Focal adhesion kinase 1 (FAK) is a ubiquitously expressed non-receptor protein tyrosine kinase that is concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents.This cellular localization is directed by a Focal Adhesion Targeting (FAT) sequence, a 125 amino acid sequence at the C-terminus.FAK plays an important role in migration, cell spreading, differentiation, cytoskeleton protein phosphorylation, apoptosis and acceleration of the G1 to S phase transition of the cell cycle.It associates with several different signaling proteins such as Src-family PTKs, p130Cas, Shc, Grb2, PI 3-kinase, and paxillin.This enables FAK to function within a network of integrin-stimulated signaling pathways leading to the activation of targets such as the ERK and JNK/mitogen-activated protein kinase pathways.FAK is also linked to oncogenes at biochemical and functional levels.Increased expression and/or activity of FAK in various tumors has been correlated with enhanced migration and invasiveness of human tumor cells in addition to promoting increased cell proliferation.
Host
Mouse
Reactivity
Human, Mouse
Applications
ELISA, WB, IHC, IF/ICC
Conjugation
Unconjugated
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