Search results for plasminogen activator

Urokinase Plasminogen Activator Surface Receptor / uPAR / CD87 (PLAUR) Antibody, Abbexa, abx033919

The urokinase-type plasminogen activator receptor is a key molecule in the regulation of cell-surface plasminogen activation and plays an important role in many normal as well as pathologic processes. The human PLAUR cDNA encodes 335 amino acids including a predicted signal peptide of 22 residues and a hydrophobic C-terminal portion.1 It produces a highly glycosylated protein of about 50 kD in monocytes where it is anchored to the plasma membrane by glycosyl-phosphatidylinositol linkage. PLAUR, also known as UPAR, is directly associated with the carbohydrate-binding domain of SELL in the membrane of neutrophils, an association analogous to that between PLAUR and beta-2 integrins.2 PLAUR-mediated calcium mobilization is SELL dependent. UPAR mRNA levels correlate with the invasive potential of endometrial carcinomas and show a 33-fold increase in UPAR mRNA levels in advanced clinical stage endometrial tumors compared with normal endometrial tissue.3 Furthermore, the increase in UPAR mRNA levels correlated linearly with the progression of disease stage. UPAR protein expressioin correlated positively with rate of recurrence and mortality in patients with endometrial cancer.4 UPAR appears to be a useful prognostic marker for advanced endometrial cancer.

Urokinase Plasminogen Activator Surface Receptor / uPAR / CD87 (PLAUR) Antibody, Abbexa, abx001219

PLAUR Antibody is a Rabbit Polyclonal antibody against PLAUR. Urokinase plasminogen activator surface receptor (uPAR, also known as PLAUR or CD87) is a 45-65 kDa, highly glycosylated, GPI-anchored membrane protein. It contains three homologous domains (D1-D3) of which the N-terminal one (D1) represents the uPA-binding domain. After binding to uPAR, urokinase plasminogen activator (uPA) cleaves plasminogen, generating the active protease plasmin which is involved in a wide variety of physiologic and pathologic processes. In addition to regulating proteolysis, uPAR has important function in cell adhesion, migration and proliferation. Studies reveal that uPAR expression is elevated during inflammation and tissue remodelling and in many human cancers, in which it frequently indicates poor prognosis. (PMID 20027185; 12461559).

Rat Urokinase Plasminogen Activator Surface Receptor (PLAUR) ELISA Kit, Abbexa, abx156207

Rat Urokinase Plasminogen Activator Surface Receptor (PLAUR) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Rat Urokinase Plasminogen Activator Surface Receptor (PLAUR) concentrations in serum, plasma and other biological fluids. This assay has high sensitivity and excellent specificity for detection of Urokinase Plasminogen Activator Surface Receptor (PLAUR)No significant cross-reactivity or interference between Urokinase Plasminogen Activator Surface Receptor (PLAUR) and analogues was observed.

Urokinase Plasminogen Activator Surface Receptor / uPAR / CD87 (PLAUR) Antibody, Abbexa, abx146428

PLAUR Antibody is a Rabbit Polyclonal against PLAUR.

Urokinase Plasminogen Activator Surface Receptor / uPAR / CD87 (PLAUR) Antibody, Abbexa, abx211254

PLAUR Antibody is a Rabbit Polyclonal against PLAUR.

Human Urokinase Plasminogen Activator Surface Receptor (PLAUR) ELISA Kit, Abbexa, abx153439

Human Urokinase Plasminogen Activator Surface Receptor (PLAUR) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Urokinase Plasminogen Activator Surface Receptor (PLAUR) concentrations in serum, plasma and other biological fluids. This assay has high sensitivity and excellent specificity for detection of Urokinase Plasminogen Activator Surface Receptor (PLAUR)No significant cross-reactivity or interference between Urokinase Plasminogen Activator Surface Receptor (PLAUR) and analogues was observed.

Mouse Urokinase Plasminogen Activator Surface Receptor (PLAUR) ELISA Kit, Abbexa, abx154828

Mouse Urokinase Plasminogen Activator Surface Receptor (PLAUR) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Urokinase Plasminogen Activator Surface Receptor (PLAUR) concentrations in serum, plasma, tissue homogenates and other biological fluids. This assay has high sensitivity and excellent specificity for detection of Urokinase Plasminogen Activator Surface Receptor (PLAUR)No significant cross-reactivity or interference between Urokinase Plasminogen Activator Surface Receptor (PLAUR) and analogues was observed.

Urokinase antibody, Genetex, GTX100465

uPAR antibody, Genetex, GTX100467

uPAR antibody [VIM5], Genetex, GTX00512