Search results for kinase 2.
Leucine Rich Repeat Kinase 2 (LRRK2) Antibody, Abbexa, abx333873
LRRK2 Antibody is a Rabbit Polyclonal against LRRK2.
Host
Rabbit
Reactivity
Human
Applications
ELISA, IHC, IF/ICC
Conjugation
Unconjugated
Death-Associated Protein Kinase 2 (DAPK2) Antibody, Abbexa, abx033134
DAPK2 belongs to the serine/threonine protein kinase family. This protein contains a N-terminal protein kinase domain followed by a conserved calmodulin-binding domain with significant similarity to that of death-associated protein kinase 1 (DAPK1), a positive regulator of programmed cell death. Overexpression of this gene was shown to induce cell apoptosis. It uses multiple polyadenylation sites.
Host
Rabbit
Reactivity
Human, Mouse
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
P21 Protein Activated Kinase 2 (PAK2) Antibody, Abbexa, abx214206
PAK2 Antibody is a Rabbit Polyclonal against PAK2.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
Homeodomain Interacting Protein Kinase 2 (HIPK2) Antibody, Abbexa, abx033461
HIPK2, a member of the KIPK subfamily of Ser/Thr protein kinases, phosphorylates homeodomain transcription factors. It may play a role as a corepressor for homeodomain transcription factors. This nuclear protein has been shown to interact with TRADD. It is highly expressed in neuronal tissues, heart and kidney, and weakly expressed in a ubiquitous way. HIPK2 is a target for sumoylation, and when conjugated it is directed to nuclear speckles.
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB
Conjugation
Unconjugated
Protein Tyrosine Kinase 2 Beta (PTK2) Antibody, Abbexa, abx011975
This gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal transduction pathways triggered in response to certain neural peptides or to cell interactions with the extracellular matrix. At least four transcript variants encoding four different isoforms have been found for this gene, but the full-length natures of only two of them have been determined. Tissue specificity: Expressed in all organs tested, in lymphoid cell lines, but most abundantly in brain.RD: Focal adhesion kinase 1 (FAK) is a ubiquitously expressed non-receptor protein tyrosine kinase that is concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. This cellular localization is directed by a Focal Adhesion Targeting (FAT) sequence, a 125 amino acid sequence at the C-terminus. FAK plays an important role in migration, cell spreading, differentiation, cytoskeleton protein phosphorylation, apoptosis and acceleration of the G1 to S phase transition of the cell cycle. It associates with several different signaling proteins such as Src-family PTKs, p130Cas, Shc, Grb2, PI 3-kinase, and paxillin. This enables FAK to function within a network of integrin-stimulated signaling pathways leading to the activation of targets such as the ERK and JNK/mitogen-activated protein kinase pathways. FAK is also linked to oncogenes at biochemical and functional levels. Increased expression and/or activity of FAK in various tumors has been correlated with enhanced migration and invasiveness of human tumor cells in addition to promoting increased cell proliferation.
Host
Mouse
Reactivity
Human
Applications
ELISA
Conjugation
Unconjugated
Protein Tyrosine Kinase 2 Beta (PTK2) Antibody, Abbexa, abx214724
PTK2 Antibody is a Rabbit Polyclonal against PTK2.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
Protein-Tyrosine Kinase 2-Beta (PYK2) Antibody, Abbexa, abx236979
PYK2 Antibody is a Rabbit Polyclonal against PYK2.
Host
Rabbit
Reactivity
Human, Mouse
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
Casein Kinase 2 Alpha 2 (CSNK2A2) Antibody, Abbexa, abx010491
Casein kinase II (CK2) is a constitutively active, ubiquitously expressed serine/threonine protein kinase that is thought to have a regulatory function in cell proliferation, cell differentiation and apoptosis. CK2 functions as a tetrameric complex consisting of two regulatory beta subunits and two catalytic units (alpha and alpha ') in a homomeric or heteromeric conformation.
Host
Mouse
Reactivity
Human, Mouse
Applications
ELISA, WB, FCM
Conjugation
Unconjugated
Human Checkpoint Kinase 2 (CHEK2) ELISA Kit, Abbexa, abx384698
Human Checkpoint Kinase 2 (CHEK2) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Checkpoint Kinase 2 (CHEK2) concentrations in tissue homogenates, cell lysates and other biological fluids.
Host
Reactivity
Human
Applications
ELISA
Conjugation
Protein Tyrosine Kinase 2 Beta (PTK2B) Antibody, Abbexa, abx333896
PTK2B Antibody is a Rabbit Polyclonal against PTK2B.
Host
Rabbit
Reactivity
Human
Applications
ELISA, IHC, IF/ICC
Conjugation
Unconjugated
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