Search results for tyrosine kinase

Protein-Tyrosine Kinase 2-Beta (PYK2) Antibody, Abbexa, abx016050
PYK2: PTK2B protein tyrosine kinase 2 beta, also known as PTK2B, PKB, PTK, CAKB, FAK2, FRNK.Entrez Protein NP_004094.It is a cytoplasmic protein tyrosine kinase which is involved in calcium-induced regulation of ion channels and activation of the map kinase signaling pathway.The encoded protein may represent an important signaling intermediate between neuropeptide-activated receptors or neurotransmitters that increase calcium flux and the downstream signals that regulate neuronal activity.The encoded protein undergoes rapid tyrosine phosphorylation and activation in response to increases in the intracellular calcium concentration, nicotinic acetylcholine receptor activation, membrane depolarization, or protein kinase C activation.This protein has been shown to bind CRK-associated substrate, nephrocystin, GTPase regulator associated with FAK, and the SH2 domain of GRB2.The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies.Four transcript variants encoding two different isoforms have been found for this gene.
Host
Mouse
Reactivity
Human
Applications
ELISA, WB, IHC
Conjugation
Unconjugated

Muscle Skeletal Receptor Tyrosine Kinase (MUSK) Antibody, Abbexa, abx145978
MUSK Antibody is a Rabbit Polyclonal against MUSK.
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB
Conjugation
Unconjugated

Discoidin Domain Receptor Tyrosine Kinase 2 (DDR2) Antibody, Abbexa, abx135978
DDR2 Antibody is a Rabbit Polyclonal against DDR2.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB
Conjugation
Unconjugated

Erb-B2 Receptor Tyrosine Kinase 2 (ERBB2) Antibody, Abbexa, abx159491
ERBB2 Antibody is a Mouse Monoclonal against ERBB2.
Host
Mouse
Reactivity
Human
Applications
ELISA, WB, IHC
Conjugation
Unconjugated

Neurotrophic Tyrosine Kinase Receptor Type 3 (NTRK3) Antibody, Abbexa, abx320137
NTRK3 Antibody is a Rabbit Polyclonal against NTRK3.
Host
Rabbit
Reactivity
Human
Applications
ELISA, IHC
Conjugation
Unconjugated

Discoidin Domain Receptor Tyrosine Kinase 2 (DDR2) Antibody, Abbexa, abx010632
DDR2 (discoidin domain receptor family, member 2) is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. Receptor tyrosine kinases (RTKs) play a key role in the communication of cells with their microenvironment. These molecules are involved in the regulation of cell growth, differentiation, and metabolism. In several cases the biochemical mechanism by which RTKs transduce signals across the membrane has been shown to be ligand induced receptor oligomerization and subsequent intracellular phosphorylation. This autophosphorylation leads to phosphorylation of cytosolic targets as well as association with other molecules, which are involved in pleiotropic effects of signal transduction. RTKs have a tripartite structure with extracellular, transmembrane, and cytoplasmic regions. This gene encodes a member of a novel subclass of RTKs and contains a distinct extracellular region encompassing a factor VIII-like domain. Alternative splicing in the 5' UTR results in multiple transcript variants encoding the same protein.
Host
Mouse
Reactivity
Human
Applications
ELISA, IHC, IF/ICC
Conjugation
Unconjugated

Human ALK Tyrosine Kinase Receptor (ALK) ELISA Kit, Abbexa, abx053422
Human ALK Tyrosine Kinase Receptor (ALK) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human ALK Tyrosine Kinase Receptor (ALK) concentrations in tissue homogenates, cell lysates and other biological fluids.
Host
Reactivity
Human
Applications
ELISA
Conjugation

TYRO Protein Tyrosine Kinase Binding Protein (TYROBP) Antibody, Abbexa, abx213626
TYROBP Antibody is a Rabbit Polyclonal against TYROBP.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, IHC
Conjugation
Unconjugated

TYRO Protein Tyrosine Kinase Binding Protein (TYROBP) Antibody, Abbexa, abx174996
This product is currently in development. The lead time for this product may be several months. Please contact us at [email protected] for an updated lead time before purchasing this product. TYRO Protein Tyrosine Kinase Binding Protein (TYROBP) Antibody is a Mouse Monoclonal antibody against TYRO Protein Tyrosine Kinase Binding Protein (TYROBP).
Host
Mouse
Reactivity
Human
Applications
WB, IHC, IF/ICC
Conjugation
Unconjugated

Human Protein Tyrosine Kinase 6 (PTK6) ELISA Kit, Abbexa, abx152891
Human Protein Tyrosine Kinase 6 (PTK6) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Protein Tyrosine Kinase 6 (PTK6) concentrations in tissue homogenates, cell lysates and other biological fluids. This assay has high sensitivity and excellent specificity for detection of Protein Tyrosine Kinase 6 (PTK6)No significant cross-reactivity or interference between Protein Tyrosine Kinase 6 (PTK6) and analogues was observed.
Host
Reactivity
Human
Applications
ELISA
Conjugation
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