Search results for erbb2
Receptor Tyrosine-Protein Kinase Erbb-2 (ERBB2) Antibody, Abbexa, abx461405
Receptor Tyrosine-Protein Kinase Erbb-2 (ERBB2) Antibody is a monoclonal Nanobody expressed in CHO cells for the detection of Human ERBB2.
Host
CHO cells
Reactivity
Human
Applications
ELISA
Conjugation
Unconjugated
Receptor Tyrosine-Protein Kinase ErbB-2 (ERBB2) Antibody, Abbexa, abx030629
This gene encodes a member of the epidermal growth factor (EGF) receptor family of receptor tyrosine kinases. This protein has no ligand binding domain of its own and therefore cannot bind growth factors. However, it does bind tightly to other ligand-bound EGF receptor family members to form a heterodimer, stabilizing ligand binding and enhancing kinase-mediated activation of downstream signalling pathways, such as those involving mitogen-activated protein kinase and phosphatidylinositol-3 kinase. Allelic variations at amino acid positions 654 and 655 of isoform a (positions 624 and 625 of isoform b) have been reported, with the most common allele, Ile654/Ile655, shown here. Amplification and/or overexpression of this gene has been reported in numerous cancers, including breast and ovarian tumors. Alternative splicing results in several additional transcript variants, some encoding different isoforms and others that have not been fully characterized.
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB
Conjugation
Unconjugated
Receptor Tyrosine-Protein Kinase ErbB-2 (ERBB2) Antibody, Abbexa, abx413370
Receptor Tyrosine-Protein Kinase ErbB-2 (ERBB2) Antibody is a Rat Monoclonal antibody against HER2/neu.
Host
Rat
Reactivity
Human
Applications
WB, IHC, FCM, IP
Conjugation
Unconjugated
Receptor Tyrosine-Protein Kinase ErbB-2 (ERBB2) Antibody, Abbexa, abx028443
Essential component of a neuregulin-receptor complex, although neuregulins do not interact with it alone. GP30 is a potential ligand for this receptor. Binds to the 5'-TCAAATTC-3' sequence in the MT-CO2 promoter and activates its transcription (By similarity).
Host
Rabbit
Reactivity
Mouse
Applications
ELISA, WB
Conjugation
Unconjugated
Receptor Tyrosine-Protein Kinase ErbB-2 (ERBB2) Antibody, Abbexa, abx033546
ErbB2, a member of the EGF receptor family, is an essential component of a neuregulin-receptor complex, although neuregulins do not interact with it alone. GP30 is a potential ligand for this receptor. This protein is not activated by EGF, TGF-alpha and amphiregulin. ErbB2 potentially forms a heterodimer with each of the other ERBB receptors. An interaction with PRKCABP has been suggested. Ligand-binding to this Type I membrane protein may increase phosphorylation on tyrosine residues.
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB, IHC, IF/ICC, FCM
Conjugation
Unconjugated
Receptor Tyrosine-Protein Kinase Erbb-2 (ERBB2) Antibody, Abbexa, abx421339
Receptor Tyrosine-Protein Kinase Erbb-2 (ERBB2) Antibody is a Mouse Monoclonal antibody for the detection of Receptor Tyrosine-Protein Kinase Erbb-2 (ERBB2) in Human samples.
Host
Mouse
Reactivity
Human
Applications
FCM
Conjugation
Unconjugated
Receptor Tyrosine-Protein Kinase ErbB-2 (Erbb2) Antibody, Abbexa, abx116600
V-Erb-B2 Erythroblastic Leukemia Viral Oncogene Homolog 2, Neuro/Glioblastoma Derived Oncogene Homolog (Avian) Antibody is a Rabbit Polyclonal antibody against V-Erb-B2 Erythroblastic Leukemia Viral Oncogene Homolog 2, Neuro/Glioblastoma Derived Oncogene Homolog (Avian).
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
Receptor Tyrosine-Protein Kinase ErbB-2 (ERBB2) Antibody, Abbexa, abx249442
HER2 Antibody is a Rabbit Polyclonal against HER2.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
WB, IHC, IF/ICC
Conjugation
Unconjugated
Receptor tyrosine-protein kinase erbB-2 (ERBB2) Antibody, Abbexa, abx326365
ERBB2 Antibody is a Rabbit Polyclonal against ERBB2.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, IF/ICC
Conjugation
Unconjugated
Receptor Tyrosine-Protein Kinase ErbB-2 (ERBB2) Antibody, Abbexa, abx413369
Receptor Tyrosine-Protein Kinase ErbB-2 (ERBB2) Antibody is a Rat Monoclonal antibody against HER2/neu.
Host
Rat
Reactivity
Human
Applications
WB, IHC, FCM, IP
Conjugation
Unconjugated
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