Search results for mitogen-activated
Mitogen-Activated Protein Kinase 9 / JNK2 (MAPK9) Antibody, Abbexa, abx033442
JNK2 responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating a number of transcription factors, primarily components of AP-1 such as c-Jun and ATF2 and thus regulates AP-1 transcriptional activity. In T-cells, JNK1 and JNK2 are required for polarized differentiation of T-helper cells into Th1 cells. JNK2 isoforms display different binding patterns: alpha-1 and alpha-2 preferentially bind to c-Jun, whereas beta-1 and beta-2 bind to ATF2. However, there is no correlation between binding and phosphorylation, which is achieved at about the same efficiency by all isoforms. JUNB is not a substrate for JNK2 alpha-2, and JUND binds only weakly to it. JNK2 is activated by threonine and tyrosine phosphorylation by either of two dual specificity kinases, MAP2K4 and MAP2K7. It is inhibited by dual specificity phosphatases, such as DUSP1. The protein has been shown to bind to at least three scaffolding proteins, MAPK8IP1/JIP-1, MAPK8IP2/JIP-2 and MAPK8IP3/JIP-3/JSAP1. These proteins also bind other components of the JNK signaling pathway.
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
Mitogen-Activated Protein Kinase 3 / ERK1 (MAPK3) Antibody, Abbexa, abx110002
Mitogen-activated protein kinase 3 Antibody is a Rabbit Polyclonal antibody against Mitogen-activated protein kinase 3.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB, IHC, IF/ICC
Conjugation
Unconjugated
Mitogen-Activated Protein Kinase 10 / JNK3 (MAPK10) Antibody, Abbexa, abx214780
MAPK10 Antibody is a Rabbit Polyclonal against MAPK10.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
Mitogen-Activated Protein Kinase 14 (MAPK14) Antibody (ATTO594), Abbexa, abx440880
p38 alpha (MAP Kinase) Antibody is a Mouse Monoclonal conjugated to ATTO 594 against p38 MAPK.
Host
Mouse
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB, IHC, IP
Conjugation
ATTO594
Mitogen-Activated Protein Kinase Kinase 2 (MAP2K2) Antibody, Abbexa, abx430727
MAP2K2 Antibody is a Goat Polyclonal antibody against MAP2K2.
Host
Goat
Reactivity
Human
Applications
P-ELISA, WB
Conjugation
Unconjugated
Mitogen Activated Protein Kinase Kinase 6 (MAP2K6) Antibody, Abbexa, abx128806
Mitogen Activated Protein Kinase Kinase 6 Antibody is a Rabbit Polyclonal against Mitogen Activated Protein Kinase Kinase 6.
Host
Rabbit
Reactivity
Human
Applications
WB, IHC, IF/ICC
Conjugation
Unconjugated
Mitogen-Activated Protein Kinase Kinase 3 (MAP2K3) Antibody, Abbexa, abx113844
Mitogen-Activated Protein Kinase Kinase 3 Antibody is a Rabbit Polyclonal antibody against Mitogen-Activated Protein Kinase Kinase 3.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB
Conjugation
Unconjugated
Mitogen-Activated Protein Kinase 8 / JNK1 (MAPK8) Antibody, Abbexa, abx000671
MAPK8 Antibody is a Rabbit Polyclonal antibody against MAPK8. The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various cell stimuli, and targets specific transcription factors, and thus mediates immediate-early gene expression in response to cell stimuli. The activation of this kinase by tumor-necrosis factor alpha (TNF-alpha) is found to be required for TNF-alpha induced apoptosis. This kinase is also involved in UV radiation induced apoptosis, which is thought to be related to cytochrom c-mediated cell death pathway. Studies of the mouse counterpart of this gene suggested that this kinase play a key role in T cell proliferation, apoptosis and differentiation. Five alternatively spliced transcript variants encoding distinct isoforms have been reported.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB, IHC, IF/ICC
Conjugation
Unconjugated
Mitogen-Activated Protein Kinase 8 / JNK1 (MAPK8) Antibody, Abbexa, abx242518
MAPK8 Antibody is a Rabbit Polyclonal against MAPK8.
Host
Rabbit
Reactivity
Human, Rat
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
Mitogen Activated Protein Kinase Kinase 6 (MAP2K6) Antibody, Abbexa, abx329023
MAP2K6 Antibody is a Rabbit Polyclonal against MAP2K6.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
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