Search results for B7

T-Lymphocyte Activation Antigen CD86 / B7-2 (CD86) Antibody, Abbexa, abx228069

CD86 antibody is a Rat monoclonal antibody against CD86.

T-Lymphocyte Activation Antigen CD86 / B7-2 (CD86) Antibody, Abbexa, abx231504

CD86 Antibody is a Rabbit Polyclonal against CD86.

T-Lymphocyte Activation Antigen CD86 / B7-2 (CD86) Antibody, Abbexa, abx028598

This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in two transcript variants encoding different isoforms. Additional transcript variants have been described, but their full-length sequences have not been determined. [provided by RefSeq].

T-Lymphocyte Activation Antigen CD86 / B7-2 (CD86) Antibody, Abbexa, abx111497

Cd86 Molecule Antibody is a Rabbit Polyclonal antibody against Cd86 Molecule.

T-lymphocyte activation antigen CD80 / B7-1 (CD80) Antibody, Abbexa, abx015727

The protein CD80 (Cluster of Differentiation 80) is a molecule found on activated B cells and monocytes which provides a costimulatory signal necessary for T cell activation and survival.It is also known as B7.1.Its principal mode of action is by binding to CD28.Along with CD86, these molecules provide the necessary stimuli to prime T cells against antigens presented by antigen-presenting cells.CD80 and CD86 also bind to CTLA-4, a cell surface molecule expressed on activated T cells.Interactions between CD80 or CD86 with CTLA-4 decrease the response of T cells.Mouse research by scientists at Emory University showed that estrogen-related bone loss is linked to recently discovered pathways involving various proteins, such as CD80 and other functions.In a nutshell, reactive oxygen stimulates dendritic cells, which activate other immune cells to up-regulate production of CD80, the molecule co-responsible for T cell activation."When this pathway is activated, it leads to increased T cell TNF production and ultimately to bone loss." In turn, T cells produce a protein, Tumor Necrosis Factor, which increases the formation of osteoclasts in rodents and humans.Osteoclasts cause minerals to be released from the bone, so that calcium is taken into the bloodstream to be used for other functions of the body.Osteoclast differentiation is inhibited by osteoprotegerin; Estrogen stimulates osteoprotegerin production.

Anti-HLA B7 antibody [EPR2623(2)] - BSA and Azide free, Abcam, AB247757

ab247757 is the carrier-free version of ab109089 . Species reactivity Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information. Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents . What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies . Conjugation ready Our carrier-free antibodies are typically supplied in a PBS-only formulation, purified and free of BSA, sodium azide and glycerol. This conjugation-ready format is designed for use with fluorochromes, metal isotopes, oligonucleotides, and enzymes, which makes them ideal for antibody labelling, functional and cell-based assays, flow-based assays (e.g. mass cytometry) and Multiplex Imaging applications. Use our conjugation kits for antibody conjugates that are ready-to-use in as little as 20 minutes with 1 minute hands-on-time and 100% antibody recovery: available for fluorescent dyes, HRP, biotin and gold. Compatibility This product is compatible with the Maxpar ® Antibody Labeling Kit from Fluidigm, without the need for antibody preparation. Maxpar ® is a trademark of Fluidigm Canada Inc.

T-lymphocyte activation antigen CD80 / B7-1 (CD80) Antibody, Abbexa, abx239881

T-lymphocyte activation antigen CD80 / B7-1 (CD80) Antibody is a Mouse Monoclonal antibody for the detection of CD80. Involved in the costimulatory signal essential for T-lymphocyte activation. T-cell proliferation and cytokine production is induced by the binding of CD28, binding to CTLA-4 has opposite effects and inhibits T-cell activation.

T-lymphocyte activation antigen CD80 / B7-1 (CD80) Antibody, Abbexa, abx414187

B-Lymphocyte Activation Antigen B7-1 (CD80) Antibody is a Mouse Monoclonal antibody against B-Lymphocyte Activation Antigen B7-1 (CD80).

Anti-Human CD274/PD-L1/B7-H1 Antibody (405.9A11), AntibodySystem, RHJ70109

Anti-Cat CD274/PD-L1/B7-H1 Polyclonal Antibody, AntibodySystem, PFJ70101